183805-10-9

Basic information

• Product Name: (S)-(+)-N-(oxiranylMethyl)acetaMide
• Synonyms: (S)-(+)-N-(oxiranylMethyl)acetaMide
• CAS NO: 183805-10-9
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.13046
• EINECS: -0
• Mol File: 183805-10-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 294.0±13.0 °C(Predicted)
• Appearance: /
• Density: 1.103±0.06 g/cm3(Predicted)
• PKA: 16.02±0.46(Predicted)
• CAS DataBase Reference: (S)-(+)-N-(oxiranylMethyl)acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-N-(oxiranylMethyl)acetaMide(183805-10-9)
• EPA Substance Registry System: (S)-(+)-N-(oxiranylMethyl)acetaMide(183805-10-9)

Safety Data

• Hazardous Substances Data: 183805-10-9(Hazardous Substances Data)

Usage

General Description

(S)-(+)-N-(oxiranylmethyl)acetamide, also known as N-[(1S)-2,2-dimethyl-1-oxiranyl]acetamide, is a chemical compound commonly used in organic synthesis. It is a chiral auxiliary that is used in the asymmetric synthesis of various organic compounds, including pharmaceuticals and natural products. (S)-(+)-N-(oxiranylMethyl)acetaMide contains an oxiranyl group, which has the potential to undergo various reactions to introduce chirality into a molecule. As a result, (S)-(+)-N-(oxiranylmethyl)acetamide is an important tool in the development of enantioselective catalysis and asymmetric synthesis. Its versatility and usefulness in organic chemistry make it a valuable compound for researchers and synthetic chemists.

Upstream product

• 474021-97-1 (S)-N-[2-(acetyloxy)-3-bromopropyl]acetamide 
• 224323-47-1 (S)-N-(3-chloro-2-hydroxy-1-propyl)acetamide 
• 183905-31-9 N-[(2S)-2-acetoxy-3-chloropropyl]acetamide 

Downstream Products

• 174649-06-0 (S)-N-[[3-[3-fluoro-4-[N-1-(4-carbobenzoxy)piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 
• 165800-03-3 linezolid 
• 1429334-02-0 N-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]acetamide 
• 1429334-00-8 (S)-N-[{3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl}methyl]acetamide 
• 174649-08-2 N-((S)-3-{4-[4-(2-Benzyloxy-acetyl)-piperazin-1-yl]-3-fluoro-phenyl}-2-oxo-oxazolidin-5-ylmethyl)-acetamide 
• 165800-04-4 eperezolid 
• 154590-66-6 (S)-N-[[3-[3-fluoro-4-(1-piperazinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 

Relevant articles and documents

Antibacterial agents

Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications, including using the invention compounds to treat bacterial infections.

OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS

Compounds of formula (I) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial P is a tricyclic ring system as defined in claiml.

Phthalamide compounds

The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) X2—CH2—C*H(OH)—CH2—NH—CO—RN??(VIIIA) and processes for production of pharmacologically useful oxazolidinones.