18381-53-8 Usage
Description
Ethyl hexafluoroglutaryl chloride, also known as 1,2,2,3,4,4-hexafluoro-1-(ethoxycarbonyl)butane, is an organofluorine compound with a molecular formula of C6H7F6O3. It is a colorless liquid with a pungent odor and is highly reactive due to the presence of the hexafluoro group. This reagent is known for its ability to form stable derivatives with various organic compounds, making it a valuable tool in analytical chemistry.
Uses
Used in Analytical Chemistry:
Ethyl hexafluoroglutaryl chloride is used as a derivatizing agent for the analysis of organic compounds in gas chromatography. Its high reactivity allows it to form stable derivatives with a wide range of compounds, improving their volatility and thermal stability, which enhances their detection and quantification in gas chromatography.
Used in Forensic Toxicology:
In the field of forensic toxicology, ethyl hexafluoroglutaryl chloride is used as a reagent for the quantification of amphetamine and methamphetamine in urine samples. The derivatization process with this reagent allows for the sensitive and accurate detection of these substances using gas chromatography/mass spectroscopy (GC/MS) techniques, which is crucial for drug testing and legal proceedings.
Used in Environmental Analysis:
Ethyl hexafluoroglutaryl chloride can also be employed in environmental analysis for the detection and quantification of various organic pollutants. Its ability to form stable derivatives with a broad range of compounds makes it a valuable tool for monitoring and assessing the presence of contaminants in air, water, and soil samples.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ethyl hexafluoroglutaryl chloride can be utilized for the synthesis of drug candidates and the development of new pharmaceutical compounds. Its reactivity and ability to form stable derivatives can aid in the creation of novel drug molecules with improved properties, such as enhanced solubility, stability, and bioavailability.
Used in Chemical Research:
Ethyl hexafluoroglutaryl chloride is also used in chemical research for the synthesis of various organofluorine compounds and the study of their properties. The unique characteristics of organofluorine compounds, such as their high reactivity and stability, make them interesting subjects for research in areas like materials science, catalysis, and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 18381-53-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,8 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18381-53:
(7*1)+(6*8)+(5*3)+(4*8)+(3*1)+(2*5)+(1*3)=118
118 % 10 = 8
So 18381-53-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClF6O3/c1-2-17-4(16)6(11,12)7(13,14)5(9,10)3(8)15/h2H2,1H3
