18385-88-1

Basic information

• Product Name: 7-methyl-2H-chromene
• Synonyms: 7-methyl-2H-chromene
• CAS NO: 18385-88-1
• Molecular Weight: 146.189
• Mol File: 18385-88-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-methyl-2H-chromene(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-2H-chromene(18385-88-1)
• EPA Substance Registry System: 7-methyl-2H-chromene(18385-88-1)

Safety Data

• Hazardous Substances Data: 18385-88-1(Hazardous Substances Data)

Downstream Products

• 3722-73-4 7-methyl chroman 

Relevant articles and documents

Synthesis of 2 h-chromenes via hydrazine-catalyzed ring-closing carbonyl-olefin metathesis

The catalytic ring-closing carbonyl-olefin metathesis (RCCOM) of O-Allyl salicylaldehydes to form 2H-chromenes is described. The method utilizes a [2.2.1]-bicyclic hydrazine catalyst and operates via a [3 + 2]/retro-[3 + 2] metathesis manifold. The nature of the allyl substitution pattern was found to be crucial, with sterically demanding groups such as adamantylidene or diethylidene offering optimal outcomes. A survey of substrate scope is shown along with a discussion of mechanism supported by DFT calculations. Steric pressure arising from syn-pentane minimization of the diethylidene moiety is proposed to facilitate cycloreversion.