18409-15-9

Basic information

• Product Name: ALPHA-NEU5AC-[2->8]-ALPHA-NEU5AC-[2->3]-BETA-D-GAL-[1->4]-D-GLC SODIUM SALT
• Synonyms: ALPHA-NEU5AC-[2->8]-ALPHA-NEU5AC-[2->3]-BETA-D-GAL-[1->4]-D-GLC SODIUM SALT;DI-[N-ACETYLNEURAMIN]LACTOSE SODIUM SALT;DISIALYLLACTOSE SODIUM SALT;disialyllactose sodium;disialyllactose sodium salt from bovine colostrum;α-neu5ac-(2→8)-α-neu5ac-(2→3)-β-d-gal-(1→4)-d-glc;(2S,4S,5R,6R)-5-acetamido-6-[(1R,2R)-2-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-1,3-dihydroxy-propyl]-2-[(2R,3S,4S,5R,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-oxan-4-yl]oxy-4-hydroxy-oxane-2-carboxylic acid;Disialyllactose
• CAS NO: 18409-15-9
• Molecular Formula: C34H56N2O27
• Molecular Weight: 924.81
• Mol File: 18409-15-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 1415.3°Cat760mmHg
• Flash Point: 809.7°C
• Appearance: /
• Density: 1.78g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.677
• Storage Temp.: −20°C
• CAS DataBase Reference: ALPHA-NEU5AC-[2->8]-ALPHA-NEU5AC-[2->3]-BETA-D-GAL-[1->4]-D-GLC SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: ALPHA-NEU5AC-[2->8]-ALPHA-NEU5AC-[2->3]-BETA-D-GAL-[1->4]-D-GLC SODIUM SALT(18409-15-9)
• EPA Substance Registry System: ALPHA-NEU5AC-[2->8]-ALPHA-NEU5AC-[2->3]-BETA-D-GAL-[1->4]-D-GLC SODIUM SALT(18409-15-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 18409-15-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C34H56N2O27/c1-9(41)35-17-11(43)3-33(31(53)54,61-26(17)19(46)13(45)5-37)60-15(7-39)21(48)27-18(36-10(2)42)12(44)4-34(62-27,32(55)56)63-28-20(47)14(6-38)58-30(24(28)51)59-25-16(8-40)57-29(52)23(50)22(25)49/h11-30,37-40,43-52H,3-8H2,1-2H3,(H,35,41)(H,36,42)(H,53,54)(H,55,56)/t11-,12-,13+,14+,15+,16+,17+,18+,19+,20-,21+,22+,23+,24+,25+,26+,27+,28-,29?,30-,33+,34-/m0/s1

Upstream product

• 489-46-3 sialic acid 
• 18409-13-7 3'-sialyllactose 

Relevant articles and documents

Sequential One-Pot Multienzyme Chemoenzymatic Synthesis of Glycosphingolipid Glycans

Glycosphingolipids are a diverse family of biologically important glycolipids. In addition to variations on the lipid component, more than 300 glycosphingolipid glycans have been characterized. These glycans are directly involved in various molecular recognition events. Several naturally occurring sialic acid forms have been found in sialic acid-containing glycosphingolipids, namely gangliosides. However, ganglioside glycans containing less common sialic acid forms are currently not available. Herein, highly effective one-pot multienzyme (OPME) systems are used in sequential for high-yield and cost-effective production of glycosphingolipid glycans, including those containing different sialic acid forms such as N-acetylneuraminic acid (Neu5Ac), N-glycolylneuraminic acid (Neu5Gc), 2-keto-3-deoxy-d-glycero-d-galacto-nononic acid (Kdn), and 8-O-methyl-N-acetylneuraminic acid (Neu5Ac8OMe). A library of 64 structurally distinct glycosphingolipid glycans belonging to ganglio-series, lacto-/neolacto-series, and globo-/isoglobo-series glycosphingolipid glycans is constructed. These glycans are essential standards and invaluable probes for bioassays and biomedical studies.