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1841081-72-8

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride is a chemical compound that is identified as an impurity in Bilastine (B385000), a novel, nonsedating H1-antihistamine medication. 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride is structurally related to the active pharmaceutical ingredient and is typically found in trace amounts within the final drug product.

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  • 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride

    Cas No: 1841081-72-8

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  • 1841081-72-8 Structure

  • Basic information

    1. Product Name: 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride
    2. Synonyms: 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride
    3. CAS NO:1841081-72-8
    4. Molecular Formula: C16H24ClN3O
    5. Molecular Weight: 309.83426
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1841081-72-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride(1841081-72-8)
    11. EPA Substance Registry System: 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride(1841081-72-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1841081-72-8(Hazardous Substances Data)

1841081-72-8 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride is used as an impurity in the development and manufacturing process of Bilastine (B385000) for the symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria. The presence of this impurity is monitored and controlled to ensure the safety, efficacy, and quality of the final drug product.
As an impurity in the pharmaceutical industry, the primary reason for its inclusion in the list of uses is to maintain the integrity of the drug development process. Impurities are critical to monitor as they can impact the overall effectiveness and safety profile of the medication. In the case of Bilastine, controlling the levels of 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride ensures that patients receive a medication that is both effective and safe for the intended use.

Check Digit Verification of cas no

The CAS Registry Mumber 1841081-72-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,4,1,0,8 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1841081-72:
(9*1)+(8*8)+(7*4)+(6*1)+(5*0)+(4*8)+(3*1)+(2*7)+(1*2)=158
158 % 10 = 8
So 1841081-72-8 is a valid CAS Registry Number.

1841081-72-8Upstream product

1841081-72-8Downstream Products

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