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5'-Cytidylic acid, 2'-O-methylis a modified form of cytidylic acid, a nucleoside monophosphate that is an essential building block of RNA. The 2'-O-methyl modification involves the addition of a methyl group to the 2' carbon of the ribose sugar in the nucleotide. This modification can affect the stability, structure, and function of RNA molecules.
Used in Research and Biotechnology Applications:
5'-Cytidylic acid, 2'-O-methylis used as a research tool for studying the effects of the 2'-O-methyl modification on RNA stability, structure, and function. This helps scientists understand the role of this modification in RNA biology and its potential applications in biotechnology.
Used in Therapeutic Applications:
5'-Cytidylic acid, 2'-O-methylis used as a therapeutic agent to modulate RNA function. The 2'-O-methyl modification can enhance the stability and functionality of RNA molecules, making them more resistant to degradation and potentially more effective in therapeutic applications. This can be particularly useful in the development of RNA-based drugs and therapies.

18422-43-0

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18422-43-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 18422-43-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,2 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18422-43:
(7*1)+(6*8)+(5*4)+(4*2)+(3*2)+(2*4)+(1*3)=100
100 % 10 = 0
So 18422-43-0 is a valid CAS Registry Number.

18422-43-0Downstream Products

18422-43-0Relevant academic research and scientific papers

Studies on the Alkylation of 5'-CMP under Alkaline Conditions

Khan, Khurshid Alam,Qudrat-e-Khuda, M.,Ahmad, Viqar Uddin

, p. 1307 - 1313 (2007/10/02)

The reaction of 5'-CMP with methyl, ethyl, n-propyl and isopropyl iodides gave predominantly ribose alkylated products.Various alkylated derivatives have been characterized using UV spectroscopy, paper electrophoresis, (1)H NMR and FAB (negative) mass spectroscopic techniques.Under strongly alkaline conditions the 2'-O-alkylated derivatives are synthesized in maximal yields.Isopropylation reaction gave only a small yield of the 3'-O-isopropyl derivative, this could be explained on the basis of steric hindrance offered to the bulky isopropyl group at the 2'-OH position by the heterocyclic base of the nucleotide. Key words: Nucleotides; ribose alkylated products; (1)H NMR spectra.

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