184221-86-1

Basic information

• Product Name: 4-broMo-8-Methoxynaphthalen-1-ol
• Synonyms: 4-broMo-8-Methoxynaphthalen-1-ol;1-Bromo-5-methoxy-4-naphthalenol
• CAS NO: 184221-86-1
• Molecular Formula: C₁₁H₉BrO₂
• Molecular Weight: 253.09196
• Mol File: 184221-86-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 51-52℃
• Appearance: /
• CAS DataBase Reference: 4-broMo-8-Methoxynaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-broMo-8-Methoxynaphthalen-1-ol(184221-86-1)
• EPA Substance Registry System: 4-broMo-8-Methoxynaphthalen-1-ol(184221-86-1)

Safety Data

• Hazardous Substances Data: 184221-86-1(Hazardous Substances Data)

Upstream product

• 3588-75-8 8-methoxy-naphthalen-1-ol 
• 83-31-8 1,8-naphthosultone 
• 569-42-6 1,8-dihydroxynaphthalene 

Downstream Products

• 1319715-16-6 C₂₀H₂₉BrO₂Si 
• 1319715-12-2 C₄₄H₅₆O₈Si 
• 1242319-39-6 C₄₂H₄₀O₈ 
• 80155-95-9 defucogilvocarcin V 
• 82196-88-1 chrysomycin A 
• 184221-88-3 4,4'-Bis-benzyloxy-5,5'-dimethoxy-[1,1']binaphthalenyl 
• 184221-87-2 4-Benzyloxy-1-bromo-5-methoxy-naphthalene 

Relevant articles and documents

SYNTHESIS OF THE POTENT IMMUNOSUPPRESSANT AGENTS DALESCONOL A AND B

This invention relates to compounds having the structure: wherein bonds α, β, γ, δ, ω, η, χ, ε, κ, and μ are each present or absent, and R1-R18 are various substituents described herein.

Total syntheses of dalesconol A and B

(Chemical equation Presented) (Chemical equation Presented) A polycyclic collapse: Use of a carefully designed acyclic intermediate participated in a cascade reaction that formed the entire core of the polyketide-derived dalesconols in a single flask (see scheme). A number of additional and carefully controlled synthetic operations completed an expeditious synthesis of both of these highly bioactive natural products as well as structural congenors.