18423-43-3

Basic information

• Product Name: Deoxythymidine triphosphate
• Synonyms: DTTP;[HYDROXY-[HYDROXY-[[3-HYDROXY-5-[(5-METHYL-2,4-DIOXO-1H-PYRIMIDIN-1-YL)]TETRAHYDROFURAN-2-YL]METHOXY]PHOSPHINOYL]OXY-PHOSPHINOYL]OXYPHOSPHONIC ACID;dTTP 2-Deoxythymidine-5-triphosphate, trisodium salt, dihydrate;thymidine 5'-triphosphate sodium;THYMIDINE 5'-TRIPHOSPHATE SODIUM 100 MM AQUEOUS SOL;THYMIDINE 5'-TRIPHOSPHATE SODIUM*PCR REA GENT;thymidine 5'-triphosphate sodium salt solution;Thymidine-5''-triphosphoric acid sodium salt
• CAS NO: 18423-43-3
• Molecular Formula: C10H17N2O13P3
• Molecular Weight: 466.17
• EINECS: 1806241-263-5
• Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Heterocycles;Nucleotides;Phosphorylating and Phosphitylating Agents;NULL
• Mol File: 18423-43-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: >0°C
• Appearance: colorless/
• Density: 1.922 g/cm³
• Storage Temp.: −20°C
• CAS DataBase Reference: Deoxythymidine triphosphate(CAS DataBase Reference)
• NIST Chemistry Reference: Deoxythymidine triphosphate(18423-43-3)
• EPA Substance Registry System: Deoxythymidine triphosphate(18423-43-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 18423-43-3(Hazardous Substances Data)

Usage

Chemical Properties

White amorphous powder

Uses

Different sources of media describe the Uses of 18423-43-3 differently. You can refer to the following data:
1. A metabolite of Thymidine (T412000). Also, a Thymidine (T412000) analogue as phosphate donor.
2. Use dTTP, lithium salt, for DNA sequencing, labeling, and all types of amplification reactions or primer-extension reactions.It has been used in PCR fingrprinting and PCR techniques.
3. dTTP, PCR Grade, is suitable for many applications where high-quality reagents are required. Such procedures include reverse transcription (RT), polymerase chain reaction (PCR), RT-PCR, DNA labeling reactions, and sequencing/cycle sequencing analysis.

General Description

dTTP is a 100 mM clear, colorless solution of lithium salt (pH 7).dTTP solution in water (pH 7), 100 mM, lithium salt.

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The rate of incorporation of labeled precursor into DNA of isolated nuclei decreased from gastrulation to the tailbud stage in developing frog embryos. The addition of saturating amounts of calf thymus DNA revealed that the activities of the enzyme(s) which incorporates deoxythymidine triphospha...detailed

Short communicationIncreased Deoxythymidine triphosphate (cas 18423-43-3) levels is a feature of relative cognitive decline08/31/2019

Mitochondrial bioenergetics, mitochondrial reactive oxygen species (ROS) and cellular levels of nucleotides have been hypothesized as early indicators of Alzheimer's disease (AD). Utilizing relative decline of cognitive ability as a predictor of AD risk, we evaluated the correlation between...detailed