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4-Chloro-2-tertbutylpyrimidine is a pyrimidine derivative with the molecular formula C9H11ClN2. It features a chlorine atom attached to the 4th carbon and a tert-butyl group attached to the 2nd carbon of the pyrimidine ring. This chemical compound serves as a versatile building block in organic synthesis, particularly in the pharmaceutical industry, and also finds use in the agrochemical and specialty chemical sectors.

18436-67-4

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18436-67-4 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-2-tertbutylpyrimidine is used as a building block for the production of various pharmaceutical drugs. Its unique structure allows for the creation of diverse drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Chloro-2-tertbutylpyrimidine is utilized as an intermediate in the synthesis of herbicides and pesticides. Its incorporation into these products contributes to their effectiveness in controlling unwanted plant growth and protecting crops.
Used in Specialty Chemicals Manufacturing:
4-Chloro-2-tertbutylpyrimidine is also employed in the manufacturing of dyes, pigments, and other specialty chemicals. Its presence in these products enhances their color and performance characteristics, making them suitable for various applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 18436-67-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,3 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18436-67:
(7*1)+(6*8)+(5*4)+(4*3)+(3*6)+(2*6)+(1*7)=124
124 % 10 = 4
So 18436-67-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H11ClN2/c1-8(2,3)7-10-5-4-6(9)11-7/h4-5H,1-3H3

18436-67-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-tert-butyl-4-chloropyrimidine

1.2 Other means of identification

Product number -
Other names 2-(tert-Butyl)-4-chloropyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18436-67-4 SDS

18436-67-4Upstream product

18436-67-4Downstream Products

18436-67-4Relevant academic research and scientific papers

Nucleophilic heteroaromatic substitution-XXIV. Kinetics of piperidinodechlorination of 2- and 6- alkyl-4-chloropyrimidines in ethanol and toluene-evidence for a steric hindrance to solvation of the aza-group

Calligaris,Linda,Marino

, p. 813 - 816 (1967)

The rate constants for the reaction of 2- and 6-alkyl-4-chloropyrimidines with piperidine in toluene and ethanol have been determined at 30.0°. The reactivity ratio kMe/kt-Bu increases considerably in passing from the reaction of 6-alkyl-4-chloropyrimidines in toluene (1.62) to the reaction of 2-alkyl-4-chloropyrimidines in ethanol (17.3). This remarkable increase (over a factor of ten) is ascribed to a steric hindrance to solvation of the aza-groups caused by the bulkier substituent.

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