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184363-66-4

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184363-66-4 Usage

General Description

(S)-4-Phenyl-3-propionyl-2-oxazolidinone is a chemical compound with the molecular formula C13H13NO3. It is a white to off-white solid with a melting point of 86-88°C. (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also known for its potential applications in organic chemistry as a building block for the creation of more complex molecules. Additionally, (S)-4-phenyl-3-propionyl-2-oxazolidinone has been studied for its biological activities, including its potential as an antibacterial and antifungal agent. Overall, this compound has a range of industrial and research applications due to its versatile chemical structure and potential pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 184363-66-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,3,6 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 184363-66:
(8*1)+(7*8)+(6*4)+(5*3)+(4*6)+(3*3)+(2*6)+(1*6)=154
154 % 10 = 4
So 184363-66-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO3/c1-2-11(14)13-10(8-16-12(13)15)9-6-4-3-5-7-9/h3-7,10H,2,8H2,1H3/t10-/m1/s1

184363-66-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S)-4-phenyl-3-propanoyl-1,3-oxazolidin-2-one

1.2 Other means of identification

Product number -
Other names (4S)-4-benzyl-3-propionyl-1,3-oxazolidin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:184363-66-4 SDS

184363-66-4Relevant articles and documents

A method for synthesis of acylated oxazolidone

-

Paragraph 0028; 0029; 0030; 0040; 0041; 0042, (2019/01/08)

The invention discloses a method for synthesis of acylated oxazolidone. Synthesis method of the invention, comprising the following steps: in the non-protic organic solvent, the compound III and under the action of an acid, the compound I with compound II carries out amidation reaction, to obtain compound IV. The method of the invention can be conducted under mild conditions, high yield, high purity, and is suitable for industrial production requirements.

Absolute configuration of lactams and oxazolidinones using kinetic resolution catalysts

Perry, Matthew A.,Trinidad, Jonathan V.,Rychnovsky, Scott D.

supporting information, p. 472 - 475 (2013/04/11)

A simple method for determining the absolute configuration of oxazolidinones, lactams, and their derivatives using kinetic resolution catalysts is described. The optically pure substrates were acylated using the (S)-HBTM and the (R)-HBTM catalyst, and the faster reaction was determined. An empirical mnemonic was developed for the assignment of the absolute configuration based on the fast-reacting catalyst.

Development of a scalable process for 1-β-methyl azetidinone: A carbapenem key intermediate

Tewari, Neera,Nizar, Hashim,Rai, Bishwa Prakash,Mane, Avinash,Prasad, Mohan

, p. 827 - 829 (2012/12/26)

An optimized process for the stereoselective synthesis of 1-β-methyl carbapenem key intermediate (3S,4S)-[(R)-1′-((tert-butyldimethylsilyl)oxy) ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone (1) and (3R,4R)-4-acetoxy-3-[(R)- 1′-((tert-butyldimethylsilyl)oxy)ethyl]-2-azetidinone has been developed employing commercially available chiral 4-phenyl-2-oxazolidinone. This method provides an efficient and cost-effective process with improved selectivity and higher yield.

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