184366-11-8Relevant academic research and scientific papers
2-Iminopyrrolidines as potent and selective inhibitors of human inducible nitric oxide synthase
Hagen, Timothy J.,Bergmanis, Arija A.,Kramer, Steven W.,Fok, Kam F.,Schmelzer, Albert E.,Pitzele, Barnett S.,Swenton, Lydia,Jerome, Gina M.,Kornmeier, Christine M.,Moore, William M.,Branson, Linda F.,Connor, Jane R.,Manning, Pamela T.,Currie, Mark G.,Hallinan, E. Ann
, p. 3675 - 3683 (2007/10/03)
A series of substituted 2-iminopyrrolidines has been prepared and shown to be potent and selective inhibitors of the human inducible nitric oxide synthase (hiNOS) isoform versus the human endothelial nitric oxide synthase (heNOS) and the human neuronal ni
