184378-04-9

Basic information

• Product Name: C₃₀H₃₂F₂N₆O₂
• Synonyms: C₃₀H₃₂F₂N₆O₂
• CAS NO: 184378-04-9
• Molecular Weight: 546.62
• Mol File: 184378-04-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₀H₃₂F₂N₆O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₀H₃₂F₂N₆O₂(184378-04-9)
• EPA Substance Registry System: C₃₀H₃₂F₂N₆O₂(184378-04-9)

Safety Data

• Hazardous Substances Data: 184378-04-9(Hazardous Substances Data)

Usage

Uses

4-[[4-[4-(4-Aminophenyl)-1-piperazinyl]phenoxy]methyl]-2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol is an impurity of (S)-Citalopram (C505005). (S)-Citalopram is an inhibitor of serotonin (5-HT) uptake. Antidepressant.

Upstream product

• 74853-08-0 1-(4-aminophenyl)-4-(4-hydroxyphenyl)piperazine 
• 1350466-82-8 C₁₄H₁₅F₂N₃O₂*ClH 
• 159276-62-7 diethyl 2-[2-(2,4-difluorophenyl)-2-propen-1-yl]-1,3-propanedioate 
• 156570-10-4 1-(1-chloromethylethenyl)-2,4-difluorobenzene 
• 1350560-52-9 C₁₆H₁₉F₂IO₃ 
• 192448-07-0 2-methylpropanoic acid [(2S)-4-(2,4-difluorophenyl)-2-hydroxymethyl-4-penten-1-yl] ester 
• 165115-73-1 2-[2-(2,4-difluorophenyl)-2-propene-1-yl]-1, 3-propanediol 
• 149809-43-8 (2R-cis)-2-(2,4-difluorophenyl)-4-[[(4-methylphenyl)sulfonyloxy]methyl]-2-[(1H-1,2,4-triazol-1-yl)methyl]tetrahydrofuran 
• 51336-94-8 2-chloro-1-(2,4-dichlorophenyl)ethanone 

Downstream Products

• 1350560-57-4 C₃₇H₄₄F₂N₈O₅ 

Relevant articles and documents

Purification of Posaconazole Intermediates

The present invention relates to a process for the purification of chiral compounds, in particular to the purification of a chiral compound of formula (XI) which may be used as intermediate for the preparation of antifungal agents, preferably posaconazole.

PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES

A process for the preparation of a chiral compound, in particular posaconazole, wherein the process comprises mixing and reacting the compounds of formula (I) Y3-NH2; of formula (Ila) 0=C=N-Y0 and/or of formula (lIb) and of formula (III) in a solvent in any order to obtain a reaction mixture containing a chiral compound of formula (IV) and/or formula (V).