18438-99-8

Basic information

• Product Name: 8-iodocoumarin
• Synonyms: 8-I-rG;8-iodocoumarin
• CAS NO: 18438-99-8
• Molecular Formula: C9H5IO2
• Molecular Weight: 272.03927
• EINECS: -0
• Mol File: 18438-99-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 785.3°Cat760mmHg
• Flash Point: 428.7°C
• Appearance: /
• Density: 2.85g/cm³
• Vapor Pressure: 5.63E-26mmHg at 25°C
• Refractive Index: 2.041
• PKA: 8.41±0.20(Predicted)
• CAS DataBase Reference: 8-iodocoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 8-iodocoumarin(18438-99-8)
• EPA Substance Registry System: 8-iodocoumarin(18438-99-8)

Safety Data

• Hazardous Substances Data: 18438-99-8(Hazardous Substances Data)

Usage

Description

8-iodocoumarin is a chemical compound derived from the coumarin family, characterized by the presence of an iodine atom in its structure. This unique feature endows it with distinct chemical and physical properties, making it a versatile reagent in organic synthesis and a promising candidate in pharmaceutical research due to its potential biological activities.

Uses

Used in Organic Synthesis:
8-iodocoumarin is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, facilitating various organic synthesis reactions. Its iodine atom plays a crucial role in these reactions, enhancing the compound's reactivity and selectivity.
Used in Pharmaceutical Research:
8-iodocoumarin is used as a subject of interest in pharmaceutical research due to its potential biological activities, including antifungal, antiviral, and antitumor properties. Its diverse applications in medicinal chemistry make it a valuable compound for the development of new drugs and therapies.
Used in Antifungal Applications:
8-iodocoumarin is used as an antifungal agent, exhibiting activity against various fungal species. Its unique structure allows it to target and inhibit essential fungal processes, making it a potential candidate for the development of new antifungal drugs.
Used in Antiviral Applications:
8-iodocoumarin is used as an antiviral agent, showing potential to inhibit viral replication and infection. Its ability to interfere with viral processes makes it a promising compound for the development of new antiviral therapies.
Used in Antitumor Applications:
8-iodocoumarin is used as an antitumor agent, demonstrating potential to inhibit tumor growth and progression. Its unique structure and biological activities make it a valuable compound for the development of new cancer treatments and therapies.

InChI:InChI=1/C10H12IN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20)