1844-41-3Relevant academic research and scientific papers
Syntheses, in vitro evaluation and molecular docking studies of 5-bromo-2-aryl benzimidazoles as α-glucosidase inhibitors
Arshad, Tanzila,Khan, Khalid Mohammed,Rasool, Najma,Salar, Uzma,Hussain, Shafqat,Tahir, Tehreem,Ashraf, Mohammed,Wadood, Abdul,Riaz, Muhammad,Perveen, Shahnaz,Taha, Muhammad,Ismail, Nor Hadiani
, p. 2058 - 2069 (2016)
Based on the previous reports on α-glucosidase inhibitory activity of benzimidazole class, we intend to evaluate further this class as potential inhibitors of α-glucosidase enzyme. Thus, in the current study synthesis of 5-bromo-2-aryl benzimidazole deriv
6,7-Dihydrobenzo[f]benzo[4,5]imidazo[1,2-d][1,4]oxazepine derivatives as selective inhibitors of PI3Kα
Yin, Yong,Zhang, Yan-Qing,Jin, Biao,Sha, Shao,Wu, Xun,Sangani, Chetan B.,Wang, She-Feng,Qiao, Fang,Lu, Ai-Min,Lv, Peng-Cheng,Zhu, Hai-Liang
, p. 1231 - 1240 (2015/03/04)
Twenty eight 6,7-dihydrobenzo[f]benzo[4,5]imidazo[1,2-d][1,4]oxazepine derivatives were synthesized and evaluated their biological activities as PI3K inhibitors. Biological evaluation against four human tumor cell lines revealed that most target compounds
Aroyl[bis(4-hydroxycoumarin-3-yl)]methanes in reactions with 1,2-diaminobenzenes
Kolos,Gozalishvili,Yaremenko,Shishkin,Shishkina,Konovalova
, p. 2277 - 2283 (2008/09/20)
The reaction of aroyl[bis(4-hydroxycoumarin-3-yl)]methanes with 1,2-phenylenediamines in PriOH is accompanied by the recyclization to 8-R-or 7-R-4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-ones, whereas the reaction with o-phenylenediamine and its
