18443-05-5Relevant academic research and scientific papers
Reduction of 1,2,3,4-Tetrahydro-γ-carbolines with Alkali Metal Borohydrides in Trifluoroacetic Acid
Kucherova, N. F.,Sipilina, N. M.,Novikova, N. N.,Silenko, I. D.,Rozenberg, S. G.,Zagorevskii, V. A.
, p. 1051 - 1053 (2007/10/02)
A preparative method for the synthesis of 9-(2,2,2-trifluoroethyl)-1,2,3,4,4a,9a-hexahydro-γ-carbolines by the action of alkali metal borohydrides in trifluoroacetic acid on 1,2,3,4-tetrahydro-γ-carbolines was developed.The indicated trifluoroethyl derivatives can also be obtained by reaction of the same reagents with 1,2,3,4,4a,9a-hexahydro-γ-carbolines, which are intermediates in the overall reduction-trifluoroethylation process.
