184530-14-1

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 123-38-6 propionaldehyde 
• 109-77-3 malononitrile 

Downstream Products

• 184530-25-4 2-amino-6-[2-(3,4-dichloro-phenyl)-2-oxo-ethylsulfanyl]-4-ethyl-pyridine-3,5-dicarbonitrile 
• 184530-17-4 2-(6-amino-3,5-dicyano-4-ethyl-pyridin-2-ylsulfanyl)-N-(4-bromo-phenyl)-acetamide 
• 184530-24-3 (6-amino-3,5-dicyano-4-ethyl-pyridin-2-ylsulfanyl)-acetic acid benzyl ester 
• 184530-18-5 2-(6-amino-3,5-dicyano-4-ethyl-pyridin-2-ylsulfanyl)-N-phenyl-acetamide 
• 184530-34-5 3,6-diamino-2-benzoyl-4-ethylthieno[2,3-b]pyridine-5-carbonitrile 
• 184530-23-2 2-amino-4-ethyl-6-(2-oxo-2-p-tolyl-ethylsulfanyl)-pyridine-3,5-dicarbonitrile 
• 184530-22-1 2-amino-4-ethyl-6-(2-oxo-2-phenyl-ethylsulfanyl)-pyridine-3,5-dicarbonitrile 

Relevant academic research and scientific papers

Synthesis of 2,6-diamino-3,5-dicyano-4-ethyl-4H-thiopyran and its recyclization to 6-amino-3,5-dicyano-4-ethylpyridine-2(1H)-thione

The triple condensation of propionaldehyde, malononitrile, and cyanothioacetamide gives 2,6-diamino-3,5-dicyano-4-ethyl-4H-thiopyran, which recyclizes to give 6-amino-3,5-dicyano-4-ethylpyridine-2(1H)-thione. This thione was used to synthesize substituted 2-alkylthiopyridines and the corresponding thieno[2,3-b]pyridines. 1997 Plenum Publishing Corporation.