18462-31-2

Basic information

• Product Name: 3β-hydroxy-13α-methylandrost-5-en-17-one acetate
• Synonyms: 3β-hydroxy-13α-methylandrost-5-en-17-one acetate
• CAS NO: 18462-31-2
• Molecular Weight: 330.467
• Mol File: 18462-31-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3β-hydroxy-13α-methylandrost-5-en-17-one acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-hydroxy-13α-methylandrost-5-en-17-one acetate(18462-31-2)
• EPA Substance Registry System: 3β-hydroxy-13α-methylandrost-5-en-17-one acetate(18462-31-2)

Safety Data

• Hazardous Substances Data: 18462-31-2(Hazardous Substances Data)

Upstream product

• 53-43-0 dehydroepiandrosterone 
• 108-24-7 acetic anhydride 
• 6585-68-8 3β-Acetoxy-5α,6α-epoxy-5α-androstanon-(17) 
• 154592-38-8 C₂₈H₃₅NO₄ 
• 51673-57-5 C₂₉H₃₇NO₆ 
• 75980-86-8 3β-acetoxyandrost-5-en-17-one acetylhydrazone 

Downstream Products

• 51348-73-3 3α-hydroxy-4-chloro-13α-androst-4-en-17-one 
• 51348-73-3 3β-hydroxy-4-chloro-13α-androst-4-en-17-one 
• 18485-76-2 13α-androst-4-en-3,17-dione 
• 55706-91-7 spiro(13α-methylandrost-1,4-dien-17,2'-oxirane)-3-one 
• 55706-91-7 spiro(13α-methylandrost-1,4-dien-17,2'-oxirane)-3-one 
• 1639-43-6 5-androstene-3β,17β-diol 3-acetate 
• 53-43-0 dehydroepiandrosterone 
• 1449-61-2 3β-acetoxy-androst-5-en-7,17-dione 

Relevant articles and documents

Recycling method of positional isomer in preparation of 3beta-acetoxy-5alpha-chloro-6beta-hydroxyandrost-17-one

The invention discloses a recycling method for forming 3beta-acetoxyandrost-5-en-17-one by performing a cyclization elimination reaction by utilizing solid waste 3beta-acetoxy-6beta-chloro-5alpha-hydroxyandrost-17-one obtained in the process of an addition reaction of preparing 3beta-acetoxy-5alpha-chloro-6beta-hydroxyandrost-17-one from 3beta-acetyloxyandrost-5-en-17-one as a raw material, and performing a reduction elimination reaction. The method provided by the invention can effectively recover and reuse the by-product obtained in the preparation process of the 3beta-acetoxy-5alpha-chloro-6beta-hydroxyandrost-17-one, and the synthetic method is simple and convenient to operate, has mild reaction conditions, is environmentally friendly, and reduces the production costs of preparing the3beta-acetoxy-5alpha-chloro-6beta-hydroxyandrost-17-one from the 3beta-acetyloxyandrost-5-en-17-one.

Zinc triflate catalyzed acylation of alcohols, phenols, and thiophenols

An expedient procedure for the acylation of alcohols, phenols, and thiophenols using catalytic amount of Zn(OTf)2 is described. This procedure is highly suitable for industrial application due to use of less toxic metal as a part of catalyst, short reaction time at ambient temperature, without any racemization of chiral alcohols.

Iminyl radicals by stannane mediated cleavage of oxime esters

Despite the explosive growth in the use of radical reactions which has swept organic synthesis in the past few years, nitrogen centred radicals and iminyls in particular have not yet attracted the attention they deserve This can be traced to a large extent to a lack of convenient and mild methods for generating such species. As part of a general study of the reactivity and synthetic potential of iminyls, we recently showed that the reaction of sulfenimines with tributystannane or the Barton decarboxylation of O-carboxymethyl oximes represented useful routes to these intermediates. Another promising approach, still in its preliminary stages however, involved the reduction of oxime esters with nickel powder in acetic acid. in this Letter, we describe yet another method based on the cleavage of oxime benzoates with tin centered radicals.