184637-11-4 Usage
Description
6-Bromo-1-(tert-butyldimethylsilyl)indole is a chemical compound with the molecular formula C18H24BrNSi. It is a derivative of indole, a heterocyclic aromatic organic compound, and contains a bromine atom and a tert-butyldimethylsilyl functional group. 6-Bromo-1-(tert-butyldimethylsilyl)indole is known for its versatility in organic synthesis and its potential applications in medicinal chemistry and drug discovery.
Uses
Used in Organic Synthesis:
6-Bromo-1-(tert-butyldimethylsilyl)indole is used as a building block for the preparation of various biologically active molecules and pharmaceuticals. Its unique structure allows for the creation of a wide range of compounds with potential therapeutic properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-Bromo-1-(tert-butyldimethylsilyl)indole is used as a versatile compound for the development of new drugs. The presence of the bromine atom and the tert-butyldimethylsilyl group enables selective modifications and protection of reactive functional groups during synthetic reactions, facilitating the design and synthesis of novel pharmaceutical agents.
Used in Drug Discovery:
6-Bromo-1-(tert-butyldimethylsilyl)indole plays a crucial role in drug discovery, where it serves as a key intermediate in the synthesis of potential drug candidates. Its ability to undergo further chemical modifications and substitutions makes it a valuable component in the development of new therapeutic agents.
Used in Chemical Protection:
The tert-butyldimethylsilyl group in 6-Bromo-1-(tert-butyldimethylsilyl)indole provides protection for reactive functional groups during synthetic reactions. This feature is particularly useful in the synthesis of complex organic molecules, where selective protection and deprotection steps are often required to achieve the desired final product.
Overall, 6-Bromo-1-(tert-butyldimethylsilyl)indole is a valuable compound in the fields of organic synthesis, medicinal chemistry, and drug discovery, owing to its unique structural features and potential for further chemical modifications.
Check Digit Verification of cas no
The CAS Registry Mumber 184637-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,6,3 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 184637-11:
(8*1)+(7*8)+(6*4)+(5*6)+(4*3)+(3*7)+(2*1)+(1*1)=154
154 % 10 = 4
So 184637-11-4 is a valid CAS Registry Number.
184637-11-4Relevant articles and documents
Rhodium-catalyzed C–H functionalization of heteroarenes using indoleBX hypervalent iodine reagents
Grenet, Erwann,Das, Ashis,Caramenti, Paola,Waser, Jér?me
supporting information, p. 1208 - 1214 (2018/06/04)
The C–H indolation of heteroarenes was realized using the benziodoxolone hypervalent iodine reagents indoleBXs. Functionalization of the C–H bond in bipyridinones and quinoline N-oxides catalyzed by a rhodium complex allowed to incorporate indole rings into aza-heteroaromatic compounds. These new transformations displayed complete regioselectivity for the C-6 position of bipyridinones and the C-8 position of quinoline N-oxides and tolerated a broad range of functionalities, such as halogens, ethers, or trifluoromethyl groups.
Novel small molecule compounds, preparation method thereof and method for treating/preventing HIV-1 infected aids by using compound
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Paragraph 0048, (2017/09/26)
The invention provides novel small molecule compounds inhibiting HIV, especially HIV-1 virus infection, a preparation method thereof and a method for inhibiting HIV, especially HIV-1 virus infection, to treat/prevent aids and relevant diseases by using th
