184644-83-5 Usage
Description
Methanethiosulfonates (MTS) are sulfhydryl-reactive compounds that form mixed disulfide linkages and are commonly used to study cysteine residues on proteins. Sodium (2-sulfonatoethyl)methanethiosulfonate (MTSES) is a negatively-charged, membrane impermeant MTS. It is highly reactive with ionized thiolates but not with unionized thiols and, therefore, targets sulfhydryl groups accessible from the aqueous medium. MTSES is used to probe the structural and functional properties of native proteins, particularly those associated with membranes, including channels and transporters. In addition, charged MTS compounds like MTSES are combined with cysteine scanning mutagenesis to study non-cysteine residues.
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 184644-83-5 differently. You can refer to the following data:
1. Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.
2. Reacts specifically and rapidly with thiols to form mixed disulfides, Sodium (2-Sulfonatoethyl)methanethiosulfonate can be used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.
Check Digit Verification of cas no
The CAS Registry Mumber 184644-83-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,6,4 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 184644-83:
(8*1)+(7*8)+(6*4)+(5*6)+(4*4)+(3*4)+(2*8)+(1*3)=165
165 % 10 = 5
So 184644-83-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H8O5S3.Na/c1-10(4,5)9-2-3-11(6,7)8;/h2-3H2,1H3,(H,6,7,8);/q;+1/p-1/rC3H7NaO5S3/c1-11(5,6)10-2-3-12(7,8)9-4/h2-3H2,1H3
