(Ser(tBu)6,Azagly10)-LHRH is a modified form of the luteinizing hormone-releasing hormone (LHRH) peptide, featuring the amino acid sequence Serine (t-butyl-protected) at position 6 and Azaglycine at position 10. This modification aims to enhance the stability and bioavailability of the LHRH peptide, which plays a crucial role in the regulation of reproductive functions. The improved pharmacokinetic properties of this peptide make it a promising candidate for therapeutic applications.
184686-52-0
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Basic information
- Product Name: (Ser(tBu)6,Azagly10)-LHRH
- Synonyms: (Ser(tBu)6,Azagly10)-LHRH;(Ser(tBu)6)-Goserelin;Pyr-His-Trp-Ser-Tyr-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2
- CAS NO:184686-52-0
- Molecular Formula: C59H84N18O14
- Molecular Weight: 1269.41046
- EINECS: N/A
- Product Categories: N/A
- Mol File: 184686-52-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (Ser(tBu)6,Azagly10)-LHRH(CAS DataBase Reference)
- NIST Chemistry Reference: (Ser(tBu)6,Azagly10)-LHRH(184686-52-0)
- EPA Substance Registry System: (Ser(tBu)6,Azagly10)-LHRH(184686-52-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 184686-52-0(Hazardous Substances Data)
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184686-52-0 Usage
Uses
Used in Hormone-sensitive Cancer Treatment:(Ser(tBu)6,Azagly10)-LHRH is used as a targeted therapy for hormone-sensitive cancers, such as prostate and breast cancer. It works by binding to the LHRH receptor on cancer cells, which can lead to the inhibition of tumor growth and progression. The modification of the peptide allows for better targeting and increased effectiveness in treating these types of cancers.
Used in Pharmaceutical Industry:
(Ser(tBu)6,Azagly10)-LHRH is used as a pharmaceutical agent for the development of new treatments for hormone-sensitive cancers. The enhanced stability and bioavailability of the modified peptide make it a valuable asset in the creation of more effective and targeted therapies. This can potentially lead to improved patient outcomes and reduced side effects compared to traditional cancer treatments.
Used in Research and Development:
(Ser(tBu)6,Azagly10)-LHRH is used as a research tool for studying the mechanisms of action and potential applications of LHRH peptides in various biological processes. The modified peptide can provide valuable insights into the role of LHRH in reproductive functions and its potential as a therapeutic target for hormone-sensitive cancers. This can contribute to the advancement of knowledge in the field and the development of novel treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 184686-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,6,8 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.Calculate Digit Verification of CAS Registry Number 184686-52:
(8*1)+(7*8)+(6*4)+(5*6)+(4*8)+(3*6)+(2*5)+(1*2)=180
180 % 10 = 0
So 184686-52-0 is a valid CAS Registry Number.
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(Ser(tBu)6,Azagly10)-LHRH
