184698-65-5 Usage
Uses
1-(4-Bromomethylphenyl)-1H-pyrrole is used in preparation of substituted purinediones as MLKL inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 184698-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,6,9 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 184698-65:
(8*1)+(7*8)+(6*4)+(5*6)+(4*9)+(3*8)+(2*6)+(1*5)=195
195 % 10 = 5
So 184698-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H10BrN/c12-9-10-3-5-11(6-4-10)13-7-1-2-8-13/h1-8H,9H2
184698-65-5Relevant articles and documents
MLKL INHIBITORS
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Paragraph 0267-0268, (2018/09/26)
Purine derivatives that inhibit cellular necroptosis and/or human MLKL, pharmaceutical compositions thereof, and methods of treating an MLKL-mediated disorder with an effective amount of the compound or composition. Said MLKL-mediated disorder is pathology associated necroptosis, including ischemia-reperfusion damage, neurodegeneration, and inflammatory diseases such as acute pancreatitis, multiple sclerosis, inflammatory bowel disease, and allergic colitis.
C:Corrosive;
