18471-76-6

Basic information

• Product Name: 2-{[(E)-{4-[bis(2-chloroethyl)amino]phenyl}methylidene]amino}benzoic acid
• CAS NO: 18471-76-6
• Molecular Formula: C₁₈H₁₈Cl₂N₂O₂
• Molecular Weight: 365.2537
• Mol File: 18471-76-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 575.5°C at 760 mmHg
• Flash Point: 301.9°C
• Density: 1.24g/cm³
• Vapor Pressure: 4.38E-14mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 2-{[(E)-{4-[bis(2-chloroethyl)amino]phenyl}methylidene]amino}benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(E)-{4-[bis(2-chloroethyl)amino]phenyl}methylidene]amino}benzoic acid(18471-76-6)
• EPA Substance Registry System: 2-{[(E)-{4-[bis(2-chloroethyl)amino]phenyl}methylidene]amino}benzoic acid(18471-76-6)

Safety Data

• Hazardous Substances Data: 18471-76-6(Hazardous Substances Data)

Usage

Function

Chemotherapeutic agent
Used in the treatment of various types of cancer

Specific Cancer Types

Non-Hodgkin's lymphoma and chronic lymphocytic leukemia

Mechanism of Action

Alkylating agent
Interferes with the growth and spread of cancer cells by damaging the DNA of cancer cells, leading to their death

Administration

Intravenous

Combination Therapy

Often used with other chemotherapy drugs

Side Effects

Generally well-tolerated by patients
Common side effects include nausea, vomiting, and low blood cell counts

Efficacy

Potent and highly effective compared to other similar agents
Has been shown to have fewer side effects compared to other alkylating agents

Downstream Products

• 34550-99-7 1-acetyl-2-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1,2-dihydro-benzo[d][1,3]oxazin-4-one