184719-29-7

Upstream product

• 132151-65-6 (E)-3-methoxy-2-methylacryloyl isocyanate 
• 88287-61-0 1-Amino-2,5-anhydro-1,3-dideoxy-4,6-di-O-p-toluyl-D-ribo-hexitol hydrochloride 
• 175672-61-4 (2-deoxy-3,5-di-O-p-toluoyl-β-D-erythro-pentofuranosyl)(thymin-1-yl) methane 
• 50908-41-3 2,5-anhydro-3-deoxy-4,6-di-O-toluoyl-D-ribohexononitrile 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 170983-96-7 2,5-anhydro-3-deoxy-1-(thymin-1-yl)-D-ribo-hexitol 
• 3601-89-6 Hoffer's chlorosugar 

Relevant academic research and scientific papers

Synthesis method for preparing monomer of 3'-mercapto nucleoside analogue

The invention relates to a synthesis method for preparing a monomer of a 3'-mercapto nucleoside analogue, and more particularly, relates to a nucleoside intermediate represented as the formula (5), a method of preparing the nucleoside intermediate, a meth

[(2-deoxy-α- and β-D-erythro-pentofuranosyl)thymin-1-yl] methane derivatives as potential conformational probes for altDNA oligonucleotides

The previously unknown deoxyribonucleoside analogues 2a,b have been efficiently synthesized from commercial 1-O-methyl-2-deoxy-3,5-di-O-p-toluoyl-D-erythro-pentofuranose. The conversion of these nucleosides to the phosphoramidite derivatives 13a,b and 14a,b for subsequent incorporation into oligodeoxyribonucleotide analogues is also described.