184763-07-3 Usage
Type of compound
Derivative of azetidinecarboxylic acid
Structure
Heterocyclic compound with a four-membered ring and a carboxylic acid group
Common use
Building block in the synthesis of peptide and protein molecules
Synthesis method
Solid-phase peptide synthesis
Protecting group
FMoc (9-fluorenylmethoxycarbonyl)
Protecting group purpose
To protect the amine group of the azetidinecarboxylic acid
Deprotection
Selective deprotection under mild conditions
Field of interest
Medicinal chemistry and pharmaceutical research
Application
Modification and manipulation of peptide structures for various applications
Check Digit Verification of cas no
The CAS Registry Mumber 184763-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,7,6 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 184763-07:
(8*1)+(7*8)+(6*4)+(5*7)+(4*6)+(3*3)+(2*0)+(1*7)=163
163 % 10 = 3
So 184763-07-3 is a valid CAS Registry Number.
184763-07-3Relevant articles and documents
Methods for producing N-protected-azetidine-2-carboxylic acids
-
, (2008/06/13)
There is disclosed a method for producing an essentially enantiomerically pure N-protected-azetidine-2-carboxylic acid of formula (1): which method is characterized by: subjecting a crude enantiomerically excess N-protected-azetidine-2-carboxylic acid comprising said enantiomer represented by formula (1) in excess to the other enantiomer thereof to crystallization in an organic solvent selected from aromatic hydrocarbon, aliphatic ether, aliphatic alcohol, aliphatic ketone, aliphatic nitrile, aliphatic amide, aliphatic sulfoxide, aliphatic ester and a mixed solvent thereof, wherein R is: an optionally substituted alkyl, alicyclic or alicyclicalkyl group, an optionally substituted alkenyl group, an optionally substituted aryl group, an optionally substituted heteroaryl group, or a dialkylamino group, and absolute configuration of the asterisked asymmetric carbon atom is S or R.
