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184775-09-5

3,5-Dimethyl-4-(2,2,2-trifluoro-1-methoxy-ethyl)-1H-pyrrole-2-carboxylic acid benzyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 184775-09-5 Structure

  • Basic information

    1. Product Name: 3,5-Dimethyl-4-(2,2,2-trifluoro-1-methoxy-ethyl)-1H-pyrrole-2-carboxylic acid benzyl ester
    2. Synonyms: 3,5-Dimethyl-4-(2,2,2-trifluoro-1-methoxy-ethyl)-1H-pyrrole-2-carboxylic acid benzyl ester
    3. CAS NO:184775-09-5
    4. Molecular Formula:
    5. Molecular Weight: 341.33
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 184775-09-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3,5-Dimethyl-4-(2,2,2-trifluoro-1-methoxy-ethyl)-1H-pyrrole-2-carboxylic acid benzyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3,5-Dimethyl-4-(2,2,2-trifluoro-1-methoxy-ethyl)-1H-pyrrole-2-carboxylic acid benzyl ester(184775-09-5)
    11. EPA Substance Registry System: 3,5-Dimethyl-4-(2,2,2-trifluoro-1-methoxy-ethyl)-1H-pyrrole-2-carboxylic acid benzyl ester(184775-09-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 184775-09-5(Hazardous Substances Data)

184775-09-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 184775-09-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,7,7 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 184775-09:
(8*1)+(7*8)+(6*4)+(5*7)+(4*7)+(3*5)+(2*0)+(1*9)=175
175 % 10 = 5
So 184775-09-5 is a valid CAS Registry Number.

184775-09-5Relevant articles and documents

Synthesis of a fluorine analog of hematoporphyrin by ring closure

Omote, Masaaki,Ando, Akira,Takagi, Toshiyuki,Koyama, Mayumi,Kumadaki, Itsumaro

, p. 13961 - 13970 (1996)

Benzyl 3,5-dimethyl-2-pyrrolecarboxylate (1) was converted to 4-(2,2,2-trifluoro-1-hydroxyethyl) derivative (2) on treatment with trifluoroacetaldehyde ethyl hemiacetal in the presence of zinc chloride. After protection of the hydroxyl group with a methyl group, 2 was converted to benzyl 4-methyl-3-(2,2,2-trifluoro-1-methoxyethyl)-2-pyrrolecarboxylate (9) and benzyl 5-acetoxymethyl-3-methyl-4-(2,2,2-trifluoro-1-methoxyethyl)-2-pyrrolec arboxylate (10). Both esters were condensed to dipyrylmethane compound 11, which was debenzylated, decarboxylated, and condensed with a bottom half of the porphyrin to give hexafluorohematoporphyrin derivative 14, potentially useful for photodynamic therapy of cancer.

Synthesis of a fluorine analog of hematoporphyrin by ring closure

Omote, Masaaki,Ando, Akira,Takagi, Toshiyuki,Koyama, Mayumi,Kumadaki, Itsumaro

, p. 89 - 93 (2007/10/03)

Benzyl 3,5-dimethyl-2-pyrrolecarboxylate (1) was converted to 4-(2,2,2-trifluoro-1-hydroxyethyl) derivative (2) on treatment with trifluoro-acetaldehyde ethyl hemiacetal in the presence of zinc chloride. After protection of the hydroxy group, 2 was converted to benzyl 4-methyl-3-(2,2,2-trifluoro-1-methoxyethyl)2-pyrrolecarboxylate (9) and benzyl 5-acetoxymethyl-3-methyl-4-(2,2,2-trifluoro-1-methoxyethyl)-2-pyrrolecarboxylate (10). Both esters were condensed to a dipyrrolomethane compound (11), which was debenzylated, decarboxylated, and condensed with a bottom half of the porphyrin to give a hexafluorohematoporphyrin derivative (14), potentially useful for photodynamic therapy of cancer.

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