18480-82-5

Upstream product

• 735291-25-5 2-acetylamino-2-cyano-3-(2-bromophenyl)-5-oxo-5-phenylpentanoic acid ethyl ester 
• 22966-10-5 (E)-3-(2-bromophenyl)-1-phenylprop-2-en-1-one 
• 735291-43-7 3-acetylamino-4-(2-bromophenyl)-2-oxo-6-phenyl-1,2,3,4-tetrahydropyridine-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

3-Aryl β-carbolin-1-ones as a new class of potent inhibitors of tumor cell proliferation: Synthesis and biological evaluation

A novel three-step synthesis of 3-aryl β-carbolin-1-ones from non-indole starting materials has been developed. The two nitrogen atoms in β-carbolin-1-one were introduced efficiently by Michael addition of ethyl acetamidocyanoacetate to chalcone. The desi

Cul catalyzed N-arylation of amide as a key step for the preparation of 3-aryl β-carbolin-1-ones

An expedient synthetic route for 3-aryl β-carbolin-1-ones was developed starting from ethyl acetamidocyanoacetate and chalcone derivatives. The five- and six-membered nitrogen-containing rings in the β-carbolin-1- ones were elaborated efficiently by an in