184895-81-6Relevant articles and documents
Novel Sulfoneamide Compound and Use Thereof
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Paragraph 0060; 0063, (2019/08/14)
The present invention relates to a novel sulfonamide compound with tyrosinase and urease inhibitory effects; and uses thereof. The novel sulfonamide compound of the present invention has inhibitory effects on tyrosinase and urease, and thus may be suitabl
Relaxant effects of selected sildenafil analogues in the rat aorta
Mojzych, Mariusz,Kubacka, Monika,Mogilski, Szczepan,Filipek, Barbara,Fornal, Emilia
, p. 381 - 388 (2016/03/30)
A new series of sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazine with chiral amino group has been synthesized and characterized. The compounds were tested for their relaxant effects in the rat aorta. Evaluation of prepared derivatives demonstrated that compound (8a) is probably a non-selective phosphodiesterase (PDE) inhibitor, as it induced aortic relaxation through endothelium-independent mechanism.
Antiviral activity evaluation of pyrazolo[4,3-e][1,2,4]triazines
Mojzych, Mariusz
scheme or table, p. 698 - 702 (2012/07/01)
The main purpose of this study is to screen synthesized pyrazolo[4,3- e][1,2,4]triazine derivatives for their antiviral activity against a panel of DNA and RNA viruses. Minimum cytotoxic and minimum virus-inhibitory concentrations of these compounds were