1849-48-5

Upstream product

• 72-18-4 L-valine 
• 89-95-2 2-methyl-benzyl alcohol 
• 90-02-8 salicylaldehyde 

Downstream Products

• 154703-01-2 (S)-2-((2-hydroxybenzyl)amino)-3-methylbutanoic acid 

Relevant academic research and scientific papers

Non-decarboxylative 1,3-dipolar cycloadditions of imines of α-amino acids as a route to proline derivatives

α-Amino acids react with aryl aldehydes in the presence of N-substituted maleimides to yield stereospecific cycloadducts (3a,b) and with dimethyl fumarate to give isomeric mixtures of (4a-i) and (5a-i). The relatively low yield in the case of dimethyl fumarate is presumably due to the steric interaction between the dipolaraphile and the substituents at both ends of the dipole.

X-ray structure analysis, electronic and vibrational circular dichroism of chiral-at-metal dioxidovanadium(V) complexes with amino acids derived Schiff base ligands

Five new chiral dioxidovanadium Schiff base complexes derived from l-valine, l-leucine, l-histidine, l-threonine and d-threonine were synthesized and characterized by elemental analysis, 1H and 51V NMR and IR spectra. The absolute co

Synthesis of amino acid derivative Schiff base copper(II) complexes by microwave and wet mechanochemical methods

As resource- and time-saving and environmentally friendly synthetic methods than conventional one in a solution, microwave, and wet mechanochemical synthesis are tested for L-amino acid derivative Schiff base copper(II) complexes. Herein, we systematicall

Synthesis, protonation constants and biological activity determination of amino acid–salicylaldehyde-derived Schiff bases

Schiff bases represent a class of molecules widely studied for their importance in organic and coordination chemistry. Despite the large amount of studies on the chemical and biological properties of the Schiff bases, the different experimental conditions

Cobalt Used as a Novel and Reusable Catalyst: A New and One-Pot Synthesis of Isatin-Derived N, S -Acetals Using Substituted Isatins and Thiols

The synthesis of isatin-derived N, S -acetals using cobalt as a recyclable heterogeneous catalyst in batch and continuous flow is reported for the first time. The present protocol produced high yields, which can be observed from the reaction between ketimines and thiols. Such reactions can also be applied to a gram-scale. In addition, the catalyst is recyclable, economically-viable, and nontoxic as well as easy to prepare. The remarkable features of this new methodology are high conversion and cleaner reaction profiles.

Synthesis and structural characterization of diorganotin(IV) esters of salicylidene-amino acids

Eight diorganotin esters of salicylidene-L-tryptophan(Sal-T) and salicylidene-L-valine(Sal-V), [(n-Bu)2Sn(Sal-T)] (1), [(n-Bu)2 Sn(Sal-V)] (2), [Ph2Sn(Sal-T)] (3), [Ph 2Sn(Sal-V)] (4), [(PhCH2)2

Synthesis, characterization and properties of ternary copper(II) complexes containing reduced Schiff base N-(2-hydroxybenzyI)-α-amino acids and 1,10-phenanthroline

Ternary copper(II) complexes containing reduced Schiff base ligands (N-(2-hydroxybenzyl)-α-amino acid, where α-amino acid = glycine (H2sgly), L-alanine (H2sala) and L-valine (H 2sval)) and 1,10-phenanthroline (phen) have b

Coordination Behaviour of Biologically Active Schiff Bases of Amino Acids Towards Stannous Ion

Reaction of tin(II) methoxide with Schiff bases derived by condensation of 2-hydroxy-1-naphthaldehyde, salicylaldehyde with glycine, β-alanine, α-valine, α-iso-leucine and α-tryptophan in 1:1 molar ratio gives a new series of tin(II) complexes. The comple

REACTION OF TRIFLUOROACETIC ANHYDRIDE WITH N-(2-HYDROXYBENZYL)-α-AMINO ACIDS: AN ENTRY IN THE NEW OXAZOLOBENZOXAZINE RING SYSTEM

The diastereospecific double ring closure of N-(2-hydroxybenzyl)-α-amino acids with trifluoroacetic anhydride leads to the formation of 10a-trifluoromethyl-2,3,4,10a-tetrahydro-oxazolobenzoxazin-2(5H)-ones.The chemical structures are supp

Complexes of Cobalt(II) with Schiff Bases Derived from Salicylaldehyde and Some Amino Acids

Complexes of cobalt(II) with schiff bases derived from salicylaldehyde and the amino acids, DL-2-aminobutyric acid, L-valine, β-alanine, 3-aminobutyric acid, 4-aminobutyric acid and L-methionine have been synthesised and characterised.Magnetic and spectral data indicate the complexes to be octahedral.