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ALA-ALA-PHE-CHLOROMETHYLKETONE TFA, also known as Tripeptidyl peptidase inhibitor, is a serine protease inhibitor derived from hydrolyzable tannins. It possesses the ability to irreversibly inhibit TPPII (tripeptidyl peptidase II), a giant protease that may substitute for some proteasome functions, and reversibly inhibit Cln (TPPI). Its unique properties enable it to interact with biopolymers and macromolecules, making it a promising candidate for various applications in the pharmaceutical and research industries.

184901-82-4

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184901-82-4 Usage

Uses

Used in Pharmaceutical Industry:
ALA-ALA-PHE-CHLOROMETHYLKETONE TFA is used as a serine protease inhibitor for the inhibition of TPPII and Cln, which are involved in various cellular processes. This inhibition can be crucial in understanding the roles of these enzymes in disease progression and potentially developing targeted therapies.
Used in Research Applications:
In the field of research, ALA-ALA-PHE-CHLOROMETHYLKETONE TFA is used as a tool to study the functions and interactions of TPPII and Cln. By inhibiting these enzymes, researchers can gain insights into their roles in cellular processes and identify potential therapeutic targets for various diseases.
Used in Drug Development:
As a potent inhibitor of TPPII and Cln, ALA-ALA-PHE-CHLOROMETHYLKETONE TFA can be employed in the development of new drugs targeting these enzymes. This may lead to the creation of novel therapeutics for conditions where these enzymes play a significant role in disease progression.
Used in Proteasome Function Studies:
Since TPPII may substitute for some proteasome functions, ALA-ALA-PHE-CHLOROMETHYLKETONE TFA can be used to study the chymotrypsin-like activity of the proteasome. This can help researchers understand the interplay between proteasomes and TPPII, potentially leading to the development of drugs that target this interaction for therapeutic purposes.

Check Digit Verification of cas no

The CAS Registry Mumber 184901-82-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,9,0 and 1 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 184901-82:
(8*1)+(7*8)+(6*4)+(5*9)+(4*0)+(3*1)+(2*8)+(1*2)=154
154 % 10 = 4
So 184901-82-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H22ClN3O3/c1-10(18)15(22)20-16(23)11(2)19-13(14(21)9-17)8-12-6-4-3-5-7-12/h3-7,10-11,13,19H,8-9,18H2,1-2H3,(H,20,22,23)/t10-,11-,13-/m0/s1

184901-82-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-amino-N-[(2S)-2-[[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]amino]propanoyl]propanamide,2,2,2-trifluoroacetic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:184901-82-4 SDS

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