184969-07-1 Usage
Uses
Used in Research Applications:
[1,4'-Bipiperidine]-3-carboxamide is used as a research tool for studying the role of GABA-A receptors in various physiological and pathological conditions. Its application is crucial in understanding the mechanisms of GABAergic neurotransmission and its modulation, which can provide insights into the development of new therapeutic strategies for neurological disorders.
Used in Pharmaceutical Development:
In the pharmaceutical industry, [1,4'-Bipiperidine]-3-carboxamide is used as a potential therapeutic agent for the treatment of neurological disorders. Its antagonistic activity against GABA-A receptors makes it a promising candidate for the development of drugs targeting conditions such as epilepsy, anxiety, and addiction. However, its narrow therapeutic window and potential toxicity require careful consideration and further research to ensure its safe and effective use in clinical practice.
Check Digit Verification of cas no
The CAS Registry Mumber 184969-07-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,9,6 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 184969-07:
(8*1)+(7*8)+(6*4)+(5*9)+(4*6)+(3*9)+(2*0)+(1*7)=191
191 % 10 = 1
So 184969-07-1 is a valid CAS Registry Number.
184969-07-1Relevant academic research and scientific papers
PYRIMIDINE DERIVATIVES
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Page/Page column 32, (2010/02/14)
The present invention provides a pyrimidine derivative represented by Formula (I) [wherein Ar represents substituted or unsubstituted aryl, etc., R1 represents -NR2R3 (wherein R2 represents a hydrogen atom or su
Synthesis of substituted 4(Z)-(methoxyimino)pentyl-1-piperidines as dual NK1/NK2 inhibitors
Ting, Pauline C,Lee, Joe F,Anthes, John C,Shih, Neng-Yang,Piwinski, John J
, p. 491 - 494 (2007/10/03)
The NK1 and NK2 receptor activity of a series of 5-[(3,5-bis(trifluoromethyl)phenyl)methoxy]-3-(3,4-dichlorophenyl)-4(Z)- (methoxyimino)pentyl-1-piperidines was evaluated. Compounds 11d, 11e, 11f, 12a, and 12k were found to be our most potent inhibitors.
