184969-12-8 Usage
Chemical structure
Piperidine derivative with a Boc protecting group at the N-1 position and a 3-hydroxypiperidin-1-ylMethyl group at the N-4 position
Functional groups
Boc protecting group, hydroxyl group, piperidine rings
Appearance
Typically a solid or oily liquid, depending on the conditions
Solubility
Soluble in organic solvents such as dichloromethane, ethyl acetate, and methanol
Stability
Stable under normal laboratory conditions, but sensitive to strong acids and bases
Reactivity
Can undergo various chemical reactions, such as deprotection, substitution, and functional group transformations
Applications
Used in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceuticals and other bioactive molecules
Drug discovery
Utilized in the preparation of novel chemical entities for drug discovery and development
Safety
Handle with care, as it may have potential hazards depending on its concentration and exposure conditions. It is important to follow proper safety protocols and guidelines when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 184969-12-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,9,6 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 184969-12:
(8*1)+(7*8)+(6*4)+(5*9)+(4*6)+(3*9)+(2*1)+(1*2)=188
188 % 10 = 8
So 184969-12-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H30N2O3/c1-16(2,3)21-15(20)18-9-6-13(7-10-18)11-17-8-4-5-14(19)12-17/h13-14,19H,4-12H2,1-3H3
184969-12-8Relevant articles and documents
Synthesis of substituted 4(Z)-(methoxyimino)pentyl-1-piperidines as dual NK1/NK2 inhibitors
Ting, Pauline C,Lee, Joe F,Anthes, John C,Shih, Neng-Yang,Piwinski, John J
, p. 491 - 494 (2007/10/03)
The NK1 and NK2 receptor activity of a series of 5-[(3,5-bis(trifluoromethyl)phenyl)methoxy]-3-(3,4-dichlorophenyl)-4(Z)- (methoxyimino)pentyl-1-piperidines was evaluated. Compounds 11d, 11e, 11f, 12a, and 12k were found to be our most potent inhibitors.
