184970-27-2

Upstream product

• 26066-15-9 3-isopropoxybenzyl alcohol 

Downstream Products

• 1193782-17-0 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-methyl-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide 
• 1193782-34-1 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-methyl-3-(5-phenyl-4,5-dihydroisoxazol-3-yl)-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide 
• 1193782-18-1 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-methyl-3-(pyridin-2-ylmethyl)-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide 
• 1193782-33-0 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-3,7-dimethyl-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide 
• 1338819-94-5 (5R,7S)-8-(3-isopropoxybenzyl)-7-methyl-1-(6-methylpyridin-2-yl)-2-thia-1,8-diazaspiro[4.5]dec-3-ene 2,2-dioxide 
• 1426254-45-6 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-meth-yl-1,8-diazaspiro[4.5]dec-3-en-2-one 
• 1193783-49-1 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-methyl-3-(pyrimidin-2-yl)-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide 
• 1193783-53-7 (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-methyl-3-(pyridin-4-yl)-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide 
• 1227684-21-0 (5R,7S)-1-(cyclopropylmethyl)-8-(3-isopropoxybenzyl)-7-methyl-1,8-diazaspiro[4.5]dec-3-en-2-one 
• 1227685-31-5 (2S,4R)-4-[(3-fluorophenyl)amino]-1-(3-isopropoxybenzyl)-2-methylpiperidine-1-carbonitrile 
• 1011732-64-1 1-(3-isopropoxy-benzyl)-piperidin-4-one 

Relevant academic research and scientific papers

1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES

The present invention relates to i-benzylindole-2-carboxamide derivatives of formula I, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 1-benzylindole-2-carboxamide deriva

SPIROPIPERIDINE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHERMER’S DISEASE

The present invention is directed to spiropiperidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. T