184970-32-9

Basic information

• Product Name: 1-PYRROLIDIN-3-YL-PIPERIDINE
• Synonyms: 1-PYRROLIDIN-3-YL-PIPERIDINE;AKOS BB-9270;1-(3-PYRROLIDINYL)-PIPERIDINE;1-((R)-pyrrolidin-3-yl)piperidine dihydrochloride;1-[(3R)-pyrrolidin-3-yl]piperidine dihydrochloride;1-((R)-pyrrolidin-3-yl)piperidine;Piperidine, 1-(3-pyrrolidinyl)-;1-pyrrolidin-3-ylpiperidine dihydrochloride
• CAS NO: 184970-32-9
• Molecular Formula: C₉H₁₈N₂
• Molecular Weight: 154.25
• Mol File: 184970-32-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 231.041°C at 760 mmHg
• Flash Point: 93.837°C
• Appearance: /
• Density: 0.989g/cm³
• Vapor Pressure: 0.064mmHg at 25°C
• Refractive Index: 1.508
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-PYRROLIDIN-3-YL-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PYRROLIDIN-3-YL-PIPERIDINE(184970-32-9)
• EPA Substance Registry System: 1-PYRROLIDIN-3-YL-PIPERIDINE(184970-32-9)

Safety Data

• Hazardous Substances Data: 184970-32-9(Hazardous Substances Data)

Usage

General Description

1-Pyrrolidin-3-yl-piperidine is a chemical compound composed of a piperidine ring linked to a pyrrolidine ring. 1-PYRROLIDIN-3-YL-PIPERIDINE has been reported as a precursor in the synthesis of pharmaceuticals and is used in the development of various drugs. It is also known as an intermediate in the production of certain illicit substances, making it a controlled substance in some jurisdictions. 1-Pyrrolidin-3-yl-piperidine is listed as a Schedule II controlled substance in the United States due to its potential for abuse and addiction. It is important to handle and use this chemical with caution and in accordance with relevant regulations and safety guidelines.

InChI:InChI=1/C9H18N2/c1-2-6-11(7-3-1)9-4-5-10-8-9/h9-10H,1-8H2

Upstream product

• 110-89-4 piperidine 
• 690265-35-1 (3R)-1-(1-benzyl-pyrrolidin-3-yl)-piperidine 
• 18471-40-4 1-Benzyl-3-aminopyrrolidine 

Downstream Products

• 690265-36-2 1-[1-(4-bromo-phenyl)-pyrrolidin-3-yl]-piperidin 
• 1608129-59-4 3-piperidin-1-yl-pyrrolidine-1-carboxylic acid [5-(2-difluoromethoxyphenyl)-2H-pyrazol-3-yl]amide 
• 1608129-58-3 3-piperidin-1-yl-pyrrolidine-1-carboxylic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide 

Relevant articles and documents

COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS

The invention features compounds, pharmaceutical compositions and methods for treating patients who have an EGFR-driven cancer of Formula (I), wherein the variables are as defined herein.

3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors

The present invention relates to certain 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives that inhibit kinases, in particular VEGFR and/or PDGFR kinases. Pharmaceutical compositions comprising these compounds, methods of treating diseases mediated by kinases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing them are also disclosed.