185025-13-2

Upstream product

• 185026-31-7 (4S,5S)-4-((E)-3-Benzyloxy-propenyl)-5-[(E)-3-(4-methoxy-benzyloxy)-propenyl]-2,2-dimethyl-[1,3]dioxolane 
• 185025-14-3 (E)-3-{(4S,5S)-5-[(E)-3-(4-Methoxy-benzyloxy)-propenyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-prop-2-en-1-ol 
• 115237-15-5 diethyl (-)-(4S,5S)-4,5-O-isopropylidene-4,5-dihydroxy-2,6-octadienedioate 
• 118508-97-7 (4S,5S)-4,5-O-isopropylidene-2E,6E-octadiene-1,4,5,8-tetraol 
• 108-24-7 acetic anhydride 
• 185025-15-4 (2E,6E)-(4S,5S)-1-Benzyloxy-8-(4-methoxy-benzyloxy)-octa-2,6-diene-4,5-diol 

Relevant academic research and scientific papers

Synthesis of chiral 3E,5E-octadiene-1,2R-7R,8-tetraol frameworks by means of palladium(II)-promoted hetero-Claisen rearrangement: Mechanistic aspect

A plausible mechanism has been proposed for the exclusive formation of symmetrical dienediol such as 1,6-bis(acetoxy)-2,4-diene in palladium(II)-promoted [3,3]sigmatropic rearrangement of 3,4-bis(acetoxy)-1,5-diene system. This mechanism referred to as migration-induced intramolecular dioxanium ion switching (MIDIS) process can reasonably explain why the vicinal acetoxy groups move from 3,4-position and not to 5,6- but two directionally to 1,6-position.