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1,4-Benzodioxin-2-acetic acid, 2,3-dihydrois a chemical compound with the molecular formula C10H10O4. It is a white crystalline powder that is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. 1,4-Benzodioxin-2-aceticacid, 2,3-dihydrohas been researched for its potential pharmacological properties, including its anti-inflammatory and analgesic effects. Additionally, it has been studied for its potential use in the treatment of central nervous system disorders. However, due to its potential toxicity and environmental concerns, the use and handling of this chemical should be done with caution and in accordance with safety guidelines.

18505-92-5

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18505-92-5 Usage

Uses

Used in Pharmaceutical Industry:
1,4-Benzodioxin-2-acetic acid, 2,3-dihydrois used as a chemical intermediate for the synthesis of various drugs, contributing to the development of new medications with potential therapeutic benefits.
Used in Research and Development:
1,4-Benzodioxin-2-aceticacid, 2,3-dihydrois used as a subject of research for its potential pharmacological properties, such as anti-inflammatory and analgesic effects, and its potential use in the treatment of central nervous system disorders. This research aims to explore and understand the compound's therapeutic potential and safety profile for future applications in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 18505-92-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,0 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18505-92:
(7*1)+(6*8)+(5*5)+(4*0)+(3*5)+(2*9)+(1*2)=115
115 % 10 = 5
So 18505-92-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O4/c11-10(12)5-7-6-13-8-3-1-2-4-9(8)14-7/h1-4,7H,5-6H2,(H,11,12)

18505-92-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-dihydro-1,4-benzodioxin-2-ylacetic acid

1.2 Other means of identification

Product number -
Other names 2,3-dihydro-5-benzofuranacetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18505-92-5 SDS

18505-92-5Relevant academic research and scientific papers

Synthesis and biological activity of new anti-inflammatory compounds containing the 1,4-benzodioxine and/or pyrrole system

Harrak,Rosell,Daidone,Plescia,Schillaci,Pujol

, p. 4876 - 4890 (2008/03/12)

A series of substituted derivatives containing the 1,4-benzodioxine or pyrrole nucleus are described. All the newly synthesized compounds were examined for their in vitro and in vivo anti-inflammatory activity. Several derivatives, including (S)-2, 14 and 17, showed more anti-inflammatory activity in vivo in these assays (rat paw oedema induced by carrageenan) than the known classical anti-inflammatory agent ibuprofen, whereas other compounds like 1 were equipotent to ibuprofen. Compound 17 was the most outstanding derivative because of its remarkable in vivo anti-inflammatory activity. In this paper, we examine and discuss the structure-activity relationships and anti-inflammatory activities of these compounds.

Synthesis and antiinflammatory activity of 2,3-dihydro-1,4-benzodioxin methyl carboxylic acids

Vazquez,Rosell,Pujol

, p. 215 - 217 (2007/10/03)

Synthesis and antiinflammatory properties of new carboxylic acids containing the 2,3-dihydro-1,4-benzodioxin subunit are described. The 2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetic acid was of comparable potency to Ibuprofen, in carrageenan induced rat paw edema assay.

N-Oxacyclic-alkylpiperidines as psychostimulants

-

, (2008/06/13)

N-Oxacyclic-alkylpiperidyl-diazacompounds, e.g., those of the formula STR1 and salts thereof are antidepressants and psychostimulants.

2-Piperidinoalkyl-1,4-benzodioxans

-

, (2008/06/13)

2-Piperidinoalkyl-1,4-benzodioxans, e.g. those of the formula STR1 AND ACID ADDITION SALTS THEREOF ARE NEUROLEPTIC AGENTS.

Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans

-

, (2008/06/13)

2-Piperidinoalkyl-1,4-benzodioxans, e.g. those of the formula STR1 and acid addition salts thereof are neuroleptic agents.

2-Piperidinoalkyl-1,4-benzodioxans

-

, (2008/06/13)

2-Piperidinoalkyl-1,4 benzodioxans, e.g. those of the formula STR1 AND ACID ADDITION SALTS THEREOF ARE NEUROLEPTIC AGENTS.

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