Decarboxy Fexofenadine is a photodegradation product of Fexofenadine (F322490), which is the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist. It is formed through the process of photodegradation, which involves the breakdown of a chemical compound by the action of light.
185066-37-9
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Basic information
- Product Name: Decarboxy Fexofenadine
- Synonyms: Decarboxy Fexofenadine;(1RS)-4-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]-1-[4-(1-methylethyl)phenyl]butan-1-ol;4-[4-(Hydroxydiphenylmethyl)piperidinyl]-1-(p-isopropylphenyl)butane-1-ol hydrochloride;Fexofenadine EP Impurity C;4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]-1-(4-propan-2-ylphenyl)butan-1-ol;Fexofenadine hydrochloride impurity C (EP)
- CAS NO:185066-37-9
- Molecular Formula: C31H39NO2
- Molecular Weight: 457.64686
- EINECS: N/A
- Product Categories: Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File: 185066-37-9.mol
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Chemical Properties
- Melting Point: 173 °C
- Boiling Point: 618.6±55.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.097±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer, Under inert atmosphere
- Solubility: DMSO (Slightly), Methanol (Slightly)
- PKA: 13.32±0.29(Predicted)
- CAS DataBase Reference: Decarboxy Fexofenadine(CAS DataBase Reference)
- NIST Chemistry Reference: Decarboxy Fexofenadine(185066-37-9)
- EPA Substance Registry System: Decarboxy Fexofenadine(185066-37-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 185066-37-9(Hazardous Substances Data)
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185066-37-9 Usage
Uses
Used in Pharmaceutical Industry:Decarboxy Fexofenadine is used as an active metabolite for the development of H1-histamine receptor antagonists. As a result of its interaction with the H1-histamine receptor, it helps in the treatment of various allergic conditions, such as allergic rhinitis and chronic idiopathic urticaria, by reducing the symptoms associated with histamine release.
Used in Research and Development:
Decarboxy Fexofenadine is used as a research compound for studying the effects of photodegradation on pharmaceutical compounds. This knowledge can be applied to improve the stability and shelf life of drugs, as well as to understand the potential implications of photodegradation on the efficacy and safety of medications.
Used in Environmental Applications:
Decarboxy Fexofenadine can be used as a model compound to study the environmental impact of pharmaceuticals and their degradation products. This information can help in the development of strategies to minimize the environmental footprint of pharmaceuticals and to ensure the safety of ecosystems exposed to these compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 185066-37-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,0,6 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.Calculate Digit Verification of CAS Registry Number 185066-37:
(8*1)+(7*8)+(6*5)+(5*0)+(4*6)+(3*6)+(2*3)+(1*7)=149
149 % 10 = 9
So 185066-37-9 is a valid CAS Registry Number.
185066-37-9 Well-known Company Product Price
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Sigma-Aldrich
(Y0000753) Fexofenadine impurity C European Pharmacopoeia (EP) Reference Standard
185066-37-9
Y0000753
1,880.19CNY
- Detail
USP
(1270446) Fexofenadine Related Compound C United States Pharmacopeia (USP) Reference Standard
185066-37-9
1270446-15MG
14,578.20CNY
- Detail
185066-37-9Upstream product
185066-37-9Downstream Products
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Decarboxy Fexofenadine
