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[[(E)-4-oxo-4-phenyl-but-2-enoyl]amino]thiourea, also known as PTUPB, is a synthetic compound with potential anticancer properties. It has been found to inhibit the growth of various cancer cell lines, including breast, colon, and prostate cancer cells, and has shown promise as a potential treatment for these types of cancer. PTUPB works by targeting and disrupting the signaling pathways involved in cancer cell proliferation and survival, making it a promising candidate for further development as a potential anticancer drug. Its mechanism of action involves inhibiting the enzyme thioredoxin reductase, which plays a critical role in cell survival and proliferation. [[(E)-4-oxo-4-phenyl-but-2-enoyl]amino]thiourea has the potential to be a valuable tool in cancer research and may lead to the development of novel treatment strategies for various types of cancer.

18507-29-4

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18507-29-4 Usage

Uses

Used in Anticancer Applications:
[[(E)-4-oxo-4-phenyl-but-2-enoyl]amino]thiourea is used as an anticancer agent for inhibiting the growth of various cancer cell lines, such as breast, colon, and prostate cancer cells. It modulates the signaling pathways involved in cancer cell proliferation and survival, exerting inhibitory effects on tumor growth and progression.
Used in Cancer Research:
[[(E)-4-oxo-4-phenyl-but-2-enoyl]amino]thiourea is used as a research tool for studying the mechanisms of cancer cell proliferation and survival. Its ability to inhibit the enzyme thioredoxin reductase makes it a valuable compound for understanding the role of this enzyme in cancer development and for exploring potential novel treatment strategies.
Used in Drug Development:
[[(E)-4-oxo-4-phenyl-but-2-enoyl]amino]thiourea is used as a potential candidate for the development of new anticancer drugs. Its mechanism of action and effectiveness against various cancer cell lines make it a promising starting point for the creation of novel therapeutics to combat cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 18507-29-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,0 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18507-29:
(7*1)+(6*8)+(5*5)+(4*0)+(3*7)+(2*2)+(1*9)=114
114 % 10 = 4
So 18507-29-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N3O2S/c12-11(17)14-13-10(16)7-6-9(15)8-4-2-1-3-5-8/h1-7H,(H,13,16)(H3,12,14,17)/b7-6+

18507-29-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name [[(E)-4-oxo-4-phenylbut-2-enoyl]amino]thiourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:18507-29-4 SDS

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