185077-02-5 Usage
General Description
3-Fluoro-2-methylphenylmagnesium bromide is a chemical compound with the formula C7H6BrF Mg. It is an organometallic reagent commonly used in organic synthesis as a source of the 3-fluoro-2-methylphenyl group. 3-FLUORO-2-METHYLPHENYLMAGNESIUM BROMID& is prepared by reacting 3-fluoro-2-methylbromobenzene with magnesium metal in a suitable solvent such as diethyl ether or tetrahydrofuran. It is used as a reactant in various synthetic reactions, particularly in the formation of carbon-carbon bonds through Grignard reactions. The reagent is also useful in the preparation of a variety of pharmaceuticals, agrochemicals, and other functional organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 185077-02-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,0,7 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 185077-02:
(8*1)+(7*8)+(6*5)+(5*0)+(4*7)+(3*7)+(2*0)+(1*2)=145
145 % 10 = 5
So 185077-02-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F.BrH.Mg/c1-6-4-2-3-5-7(6)8;;/h2,4-5H,1H3;1H;/q;;+1/p-1/rC7H6BrFMg/c1-5-2-3-6(10-8)4-7(5)9/h2-4H,1H3
185077-02-5Relevant articles and documents
7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS
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Page/Page column 21, (2010/02/11)
The invention provides one or more chemical entities selected from a compound of formula (I): (I) wherein R1 represents C1-6alkyl, trifluoromethoxy or halo; R2 represents hydrogen, C1-6alkyl or halo; or when R1 and R2 are positioned at the 3- and 4-positions, R1 and R2 together with the carbon atoms to which they are attached may form a 1,4-dioxane ring; and a pharmaceutically acceptable salt and solvate thereof. The compounds of formula (I) and pharmaceutically acceptable salts and solvates thereof are useful in therapy, in particular as antipsychotic agents.
