1851373-36-8 Usage
Uses
3-[[[(1R)-1,2,3,4-Tetrahydro-6-(methylphenylamino)-1-naphthalenyl]methyl]amino]-4-Pyridinecarboxylic Acid is also known as a KDM4 inhibitor exhibiting antiproliferative effects in cancer models.
Check Digit Verification of cas no
The CAS Registry Mumber 1851373-36-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,5,1,3,7 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1851373-36:
(9*1)+(8*8)+(7*5)+(6*1)+(5*3)+(4*7)+(3*3)+(2*3)+(1*6)=178
178 % 10 = 8
So 1851373-36-8 is a valid CAS Registry Number.
1851373-36-8Relevant articles and documents
KDM4 INHIBITORS
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Paragraph 00143; 00144, (2018/10/25)
The present disclosure relates generally to compounds and methods for inhibiting the enzymatic activity of lysine demethylase 4 (KDM4) and treating cancer. Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibiting lysine demethylase 4. Furthermore, the subject compounds and compositions are useful for the treatment of breast cancer and the like.
