1852-41-1

Basic information

• Product Name: ANDROSTERONE SULFATE SODIUM CRYSTALLINE
• Synonyms: ANDROSTERONE SULFATE SODIUM CRYSTALLINE;Androsterone sulfate sodium salt;SodiuM 5a-Androstan-3a-ol-17-one-d2 Sulfate;3α-Hydroxy-5α-androstan-17-one 3-sulfate;5α-Androstan-3α-ol-17-one sulfate
• CAS NO: 1852-41-1
• Molecular Formula: C₁₉H₂₉O₅S*Na
• Molecular Weight: 392.48533
• Mol File: 1852-41-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 144 °C
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ANDROSTERONE SULFATE SODIUM CRYSTALLINE(CAS DataBase Reference)
• NIST Chemistry Reference: ANDROSTERONE SULFATE SODIUM CRYSTALLINE(1852-41-1)
• EPA Substance Registry System: ANDROSTERONE SULFATE SODIUM CRYSTALLINE(1852-41-1)

Safety Data

• Hazardous Substances Data: 1852-41-1(Hazardous Substances Data)

Usage

General Description

Androsterone Sulfate Sodium Crystalline is a steroid hormone and a sulfated derivative of androsterone. It is a crystalline powder form of the hormone that is commonly used in scientific research and medical studies. Androsterone itself is a steroid that is produced in the body from the metabolism of testosterone and has various biological effects, including being involved in the regulation of male reproductive function and behavior. The sulfate form of androsterone is a water-soluble derivative that can be easily utilized in laboratory experiments and pharmaceutical applications. Overall, Androsterone Sulfate Sodium Crystalline is a valuable chemical compound that plays a crucial role in the study and understanding of hormonal physiology and related medical conditions.

Upstream product

• 53-41-8 cis-androsterone 

Relevant articles and documents

5α-Androst-16-en-3α-ol β-D-glucuronide, precursor of 5α-androst-16-en-3α-ol in human sweat

5α-Androst-16-en-3α-ol (α-androstenol) is an important contributor to human axilla sweat odor. It is assumed that α-andostenol is excreted from the apocrine glands via a H2O-soluble conjugate, and this precursor was formally characterized in this study for the first time in human sweat. The possible H2O-soluble precursors, sulfate and glucuronide derivatives, were synthesized as analytical standards, i.e., α-androstenol, β-androstenol sulfates, 5α-androsta-5,16-dien- 3β-ol (β-androstadienol) sulfate, α-androstenol β-glucuronide, α-androstenol α-glucuronide, β-androstadienol β-glucuronide, and α-androstenol β-glucuronide furanose. The occurrence of α-androstenol β-glucuronide was established by ultra performance liquid chromatography (UPLC)/MS (heated electrospray ionization (HESI)) in negative-ion mode in pooled human sweat, containing eccrine and apocrine secretions and collected from 25 female and 24 male underarms. Its concentration was of 79 ng/ml in female secretions and 241 ng/ml in male secretions. The release of α-androstenol was observed after incubation of the sterile human sweat or α-androstenol β-glucuronide with a commercial glucuronidase enzyme, the urine-isolated bacteria Streptococcus agalactiae, and the skin bacteria Staphylococcus warneri DSM 20316, Staphylococcus haemolyticus DSM 20263, and Propionibacterium acnes ATCC 6919, reported to have β-glucuronidase activities. We demonstrated that if α- and β-androstenols and androstadienol sulfates were present in human sweat, their concentrations would be too low to be considered as potential precursors of malodors; therefore, the H2O-soluble precursor of α-androstenol in apocrine secretion should be a β-glucuronide. Copyright