185202-26-0Relevant articles and documents
Synthesis of 10,11-dihydro-12-oxo-LTB4, a key biochemical intermediate
Khanapure, Subhash P.,Wang, Steven S.,Powell, William S.,Rokach, Joshua
, p. 325 - 330 (1997)
The first total synthesis of the 5(S)-hydroxy-10,11-dihydro-12-oxo-6(Z),8(E),14(Z)-eicosatrienoic acid (10,11-dihydro-12-oxo-LTB4) (3) is reported. This compound is a key pivotal intermediate in the biotransformation of LTB4 by the so-called 'LTB4 reductase pathway'.