185219-02-7

Basic information

• Product Name: 4-(4-Amino-6-chloropyrimidin-2-ylsulfanyl)-N,N-diethyl-2(E)-butenamide
• CAS NO: 185219-02-7
• Molecular Formula: C₁₂H₁₇ClN₄OS
• Molecular Weight: 300.81249
• Mol File: 185219-02-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-Amino-6-chloropyrimidin-2-ylsulfanyl)-N,N-diethyl-2(E)-butenamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Amino-6-chloropyrimidin-2-ylsulfanyl)-N,N-diethyl-2(E)-butenamide(185219-02-7)
• EPA Substance Registry System: 4-(4-Amino-6-chloropyrimidin-2-ylsulfanyl)-N,N-diethyl-2(E)-butenamide(185219-02-7)

Safety Data

• Hazardous Substances Data: 185219-02-7(Hazardous Substances Data)

Relevant articles and documents

Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase

The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula (I) and pyrimidine-thioalkyl and alkylethers of Formula (IA), namely the compounds of Formula (I) where R 4 is selected from the group consisitng of --H or --NR 15 R 16 where R 15 is --H and R 16 is --H, C 1 -C 6 alkyl, NH 2 or R 15 and R 16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R 6 is selected from the group consisting of --H, or halo (preferably --Cl); with the overall proviso that R 4 and R 6 are not both --H. The compounds of Formula (IA) are useful in the treatment of individuals who are HIV positive being inhibitors of viral reverse transcriptase. STR1