18530-09-1

Basic information

• Product Name: (2alpha,5alpha,10alpha)-2,9,10-tris(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2Z)-3-phenylprop-2-enoate - N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide (1:1)
• CAS NO: 18530-09-1
• Molecular Formula: C₂₆H₃₆O₈
• Molecular Weight: 983.368020000001
• Mol File: 18530-09-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2alpha,5alpha,10alpha)-2,9,10-tris(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2Z)-3-phenylprop-2-enoate - N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: (2alpha,5alpha,10alpha)-2,9,10-tris(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2Z)-3-phenylprop-2-enoate - N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide (1:1)(18530-09-1)
• EPA Substance Registry System: (2alpha,5alpha,10alpha)-2,9,10-tris(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2Z)-3-phenylprop-2-enoate - N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide (1:1)(18530-09-1)

Safety Data

• Hazardous Substances Data: 18530-09-1(Hazardous Substances Data)

Upstream product

• 189956-94-3 taxine NA-1 
• 3835-52-7 taxinine 

Downstream Products

• 18530-10-4 taxinine H 
• 204572-79-2 2.9.10-Tri-O-acetyl-11.12-didehydro-taxinol-5α-benzoat 
• 18615-53-7 taxinine K 

Relevant articles and documents

Determination of the stereochemistry of C-2' and C-3' positions of taxine NA-1 (2'-hydroxytaxine II) by the asymmetric synthesis of the reductive degradation product of its side chain moiety

The reductive degradation of taxine NA-1 (2'-hydroxytaxine II) with n-Bu4NBH4 gave taxinine A and (-)-3-dimethylamino-3- phenylpropane-1,2-diol (1) in addition to 11,12-dihydrotaxinine A. The relative stereochemistry of (-)-1 was identical with syn-3-dimethylamino-3-phenylpropane- 1,2-diol, (±)-1b, which was synthesized from cis-2,3-epoxy-3- phenylpropan-1-ol, (±)-7. The absolute configuration of (-)-1 was certified by comparison of the specific optical rotation and the spectroscopic data of (-)-1 with those of (+)-1b and (-)-1b, which were enantioselectively synthesized by Sharpless asymmetric epoxidation reaction of cis-cinnamyl alcohol (6), respectively. As the result, the relative and absolute configuration of (-)-1 was same with that of (-)-1b possessing (2R, 3S) configuration. Thus, the absolute configuration of the side chain of taxine NA-1 (2'-hydroxytaxine II) at C-2' and C-3' positions was determined to be (2'R, 3'S).