185304-90-9Relevant academic research and scientific papers
Construction of the azepinoindole core tricycle of the Stemona alkaloids
Rigby, James H.,Laurent, Stephane,Cavezza, Alexandre,Heeg, Mary Jane
, p. 5587 - 5591 (2007/10/03)
The azepinoindole substructure common to a number of Stemona alkaloids is constructed by employing a 7-endo radical cyclization of a readily available N-alkylated hydroindolone substrate. The indolone precursors are prepared via [1 + 4] cycloaddition between a vinyl isocyanate and either dimethoxycarbene or cyclohexylisocyanide.
