185342-88-5

Usage

Uses

Used in Chemical Synthesis:
1,3-Dibromo-2,4-dimethoxy-benzene is used as a starting material or an intermediate for the synthesis of other complex organic molecules. Its unique structure with bromine and methoxy groups allows for various chemical reactions and transformations, making it a valuable compound in the field of organic chemistry.
Used in Research Applications:
1,3-Dibromo-2,4-dimethoxy-benzene is used as a research compound in laboratories to study its properties and potential applications. Its reactivity, solubility, and other physical and chemical characteristics are of interest to researchers working in the field of organic chemistry and related disciplines.
Used in Pharmaceutical Industry:
1,3-Dibromo-2,4-dimethoxy-benzene is used as a building block in the development of new pharmaceutical compounds. Its unique structure and reactivity make it a promising candidate for the synthesis of novel drugs with potential therapeutic applications.
Used in Material Science:
1,3-Dibromo-2,4-dimethoxy-benzene is used in the development of new materials with specific properties, such as improved solubility, stability, or reactivity. Its incorporation into various materials can lead to the creation of innovative products with applications in different industries.

Upstream product

• 16932-45-9 1-bromo-2,6-dimethoxybenzene 
• 151-10-0 1,3-Dimethoxybenzene 
• 18011-67-1 2,4-dibromo-1,3-benzenediol 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1256544-69-0 6-(3-bromophenyl)benzofurano[2,3-c]dibenzofuran 
• 875902-97-9 1,3-dimethoxy-2,4-diformylbenzene 

Relevant academic research and scientific papers

Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors

Autophagy is a catabolic process, which mediates degradation of cellular components and has important roles in health and disease. Therefore, small molecule modulators of autophagy are in great demand. Herein, we describe a phenotypic high-content screen for autophagy inhibitors, which led to the discovery of a dimethoxypyridine-based class of autophagy inhibitors, which derive from previously reported, natural product-inspired MAP4K4 inhibitors. Comprehensive structure-activity relationship studies led to a potent compound, and biological validation experiments indicated that the mode of action was upstream or independent of mTOR.

Photocatalytic Oxidative Bromination of Electron-Rich Arenes and Heteroarenes by Anthraquinone

The estimated excited oxidation potential of sodium anthraquinone-2-sulfonate (SAS) increases from 1.8 V to about 2.3 V vs SCE by protonation with Br?nsted acids. This increased photooxidation power of protonated anthraquinone was used for the regio-selective oxidative bromination of electron rich (hetero)arenes and drugs in good yield. The mild reaction conditions are compatible with many functional groups, such as double and triple bonds, ketones, amides and amines, hydroxyl groups, carboxylic acids and carbamates. Mechanistic investigations indicate the photooxidation of the arene followed by nucleophilic bromide addition as the likely pathway. (Figure presented.).

COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

When a decrease in low-grey level region (e.g., 0 to 80 grey) efficiencies of organic light emitting devices is not constant, deviation among display panels may cause color change and stain in the low luminance region. Aspects of the present disclosure ar

HETEROCYCLIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT PREPARED USING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC APPARATUS PREPARED USING THE SAME

PROBLEM TO BE SOLVED: To provide a novel material useful as an organic electroluminescent element material. SOLUTION: This invention relates to a heterocyclic compound wherein three five-membered rings are condensed on a benzene ring, and further, saturat

ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME

An anthracene derivative represented by the following formula (1): In the formula (1), Z is a structure represented by the following formula (2). In the formula (2), at least one pair of adjacent two substituents of R11 to R18 form a ring represented by the following formula (3) or (4):

N-salicylideneanilines: Tautomers for formation of hydrogen-bonded capsules, clefts, and chains

The synthesis, characterization, and solid-state structures of new salicylaldimines are reported. Bis(N-salicylideneaniline)s (BSANs) and tris(N-salicylideneaniline)s (TSANs) are sterically encumbered compounds featuring a central six-membered ring in the

1,3-dibromo-5,5-dimethylhydantoin, a useful reagent for aromatic bromination

1,3-dibromo-5,5-dimethylhydantoin (DBDMH) is a useful and easy to handle reagent for bromination of various aromatic derivatives substituted with electron donating groups. In the presence of trimethylsilyltrifluoromethanesulfonate, DBDMH showed increased reactivity, and in one case, the reaction followed another pathway, suggesting an alternative mechanism.

Synthesis of brominated compounds. A convenient molybdenum-catalyzed procedure inspired by the mode of action of haloperoxidases

A two-phase (CHCl3/H2O) procedure for the synthesis of halogenated compounds has recently been developed. Such procedure mimics the mode of action of the enzymes haloperoxidases which contain vanadium in their active center. We have investigated the possibility to substitute vanadium with molybdenum. The molybdenum-based reactions show some advantages over the vanadium-based ones. In fact reaction times are shorter and overall yields are larger, under similar experimental conditions, both in the reaction with double bonds as well as with aromatic rings. Moreover, with double bonds, the molybdenum catalyzed process preferentially yields bromohydrins which are valuable synthetic intermediates. On the other hand, the molybdenum-catalyzed reactions show peculiar mechanistic features which deserve further investigation.