185419-99-2Relevant articles and documents
Substituted pyridazino[3,4-b][1,5] benzoxazepin-5(6H)ones as multidrug-resistance modulating agents
Ott, Ingo,Kircher, Brigitte,Heinisch, Gottfried,Matuszczak, Barbara
, p. 4627 - 4630 (2007/10/03)
Pyridazino[3,4-b][1,5]benzoxazepin-5(6H)ones substituted with propylene-linked basic side chains were synthesized and investigated for the ability to reverse multidrug resistance (MDR) at vincristine-pretreated HeLa-MDR1 cells. The substances were found t