185447-01-2Relevant academic research and scientific papers
Synthesis of 2-(trimethylsilyl)ethyl α-D-mannopyranosides revisited
Saksena, Rina,Zhang, Jian,Kovac, Pavol
, p. 453 - 470 (2007/10/03)
Glycosylation of 2-(trimethylsilyl)ethanol with various ethyl 1-thioglycosides, which were activated with N-iodosuccinimide and silver triflate, was studied. The starting thioglycosides, some prepared for the first time, were obtained conventionally from the corresponding α-1-acetates. When β-1-acetates were more readily available, these were converted to the α-anomers by anomerization, prior to the glycosylation. Using ethyl 1-thioglycosides as glycosyl donors, especially those bearing a pivaloyl or a nonparticipating group at O-2, the corresponding 2-(trimethylsilyl)ethyl α-D-mannopyranosides were obtained in excellent yields.
Stereoselective synthesis of 2-hydroxy-alpha-mannopyranosides from glucal donors.
Kim,Di Bussolo,Gin
, p. 303 - 306 (2007/10/03)
[figure: see text] Direct synthetic access to 2-hydroxy-alpha-mannopyranosides from glucal donors is accomplished via a one-pot stereoselective oxidative glycosylation reaction, employing the reagent combination of dibenzothiophene bis(triflate) and dibenzothiophene-5-oxide.
Eine orthogonale Glycosylierungsstrategie fuer den raschen Aufbau von Oligosacchariden an einem polymeren Traeger
Ito, Yukishige,Kanie, Osamu,Ogawa, Tomoya
, p. 2691 - 2693 (2007/10/03)
Keywords: Festphasensynthese; Glycoproteine; Glycosylierungen; Oligosaccharide
