185456-07-9

Upstream product

• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 3321-92-4 1-(3,5-dichloro-2-hydroxyphenyl)-ethanone 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1417797-59-1 4-(2-hydroxy-3,5-dichlorophenyl)-6-(4-chlorophenyl)-2-imino-1,3-thiazine 
• 1417797-61-5 4-(2-hydroxy-3,5-dichlorophenyl)-6-(4-chlorophenyl)-2-iminophenyl-3-phenyl-1,3-thiazine 
• 1657006-77-3 C₁₈H₁₃Br₂Cl₃O₂ 
• 1657006-97-7 C₁₈H₁₃Cl₃O₂ 

Relevant academic research and scientific papers

Synthesis and antibacterial studies of chloro-substituted 1,3-thiazines

Thiazines are very useful units in the fields of medicinal and pharmaceutical chemistry and have been reported to exhibit a variety of biological activities. This has directed us to synthesize chloro-substituted thiazines from 2'-hydroxy-3',5'-dichloro-4-

Synthesis and biological activities of some flavones

Chalcones are synthesized by a base catalyzed Claisen Schmidt condensation reaction and then treated with dimethylsulphoxide in presence of iodine to get flavones. The synthesized compounds were evaluated for their antibacterial activity against Escherichia coli, P. aeruginosa, S. epidermidis and B. subtilis. All the flavones showed moderate to good activity. The structures of these compounds were confirmed by IR, UV, 1H NMR, Mass and elemental analysis.

Synthesis of pyrazolines, isoxazoles and cyanopyridines as potential antimicrobial agents

3,5-Dichloro-2-hydroxyacetophenone 1 on treatment with aromatic aldehydes yields 3,5-dichloro-2-hydroxy-ω-arylidine acetophenones 2a-j which on cyclisation with hydrazine hydrate, hydroxylamine hydrochloride and malononitrile furnishes the corresponding 3