18546-08-2

Basic information

• Product Name: 6-Deoxy-3-O-methyl-L-altrose
• Synonyms: 6-Deoxy-3-O-methyl-L-altrose;L-Vallarose
• CAS NO: 18546-08-2
• Molecular Formula: C₇H₁₄O₅
• Molecular Weight: 178.18306
• Mol File: 18546-08-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 386.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.256±0.06 g/cm3(Predicted)
• PKA: 12.38±0.20(Predicted)
• CAS DataBase Reference: 6-Deoxy-3-O-methyl-L-altrose(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Deoxy-3-O-methyl-L-altrose(18546-08-2)
• EPA Substance Registry System: 6-Deoxy-3-O-methyl-L-altrose(18546-08-2)

Safety Data

• Hazardous Substances Data: 18546-08-2(Hazardous Substances Data)

Upstream product

• 1159579-91-5 hoodigoside W 
• 1159579-92-6 hoodigoside X 
• 1159579-93-7 calogenin 20-O-β-D-glucopyranosyl-3-O-β-D-thevetopyranosyl-(1->4)-β-D-oleandropyranoside 
• 82001-47-6 C₃₂H₄₄O₁₁ 
• 5158-60-1 methyl-(O³-methyl-6-deoxy-α-D-altropyranoside) 

Downstream Products

• 112047-81-1 O³-methyl-D-ribo-6-deoxy-[2]hexosulose-bis-phenylhydrazone 
• 112047-81-1 O³-methyl-D-arabino-6-deoxy-[2]hexosulose-bis-phenylhydrazone 

Relevant articles and documents

Four new pregnane glycosides from Gymnema latifolium and their α-glucosidase and α-amylase inhibitory activities

Four new pregnane glycosides, gymlatifosides A - D (1 ? 4) and one known pregnane glycoside, verticilloside J (5) were isolated from the leaves of Gymnema latifolium Wall. ex Wight. Their chemical structures were elucidated on the basis of extensive spectroscopic methods, including 1D, 2D NMR, HR-ESI-MS, and in comparison with the reported data. All these compounds were tested for α-glucosidase and α-amylase inhibitory activities. Compound 5 exhibited the most anti α-glucosidase activity with inhibitory percentage of 37.8 ± 1.5% at the concentration of 200 μM. Compounds 1–4 showed moderate anti α-glucosidase activity with inhibitory percentage ranging from 7.0 to 30.1%. In addition, all compounds 1–5 showed moderate/weak anti α-amylase activity in the investigated test.

Melanogenesis inhibitory pregnane glycosides from Cynanchum atratum

Bioassay-guided fractionation of the methanolic extract from the roots of Cynanchum atratum has resulted in the isolation of three new pregnane glycosides (1–3) along with four known compounds (4–7). Their structures were identified by analysis of the spectroscopic data including extensive 2D NMR. All of the isolates were evaluated for their potential to inhibit the melanin production in α-melanocyte stimulating hormone (α-MSH)-activated B16 melanoma cells. Of these, compounds 4–7 dose-dependently inhibited the melanin production with the IC50 values ranging from 4 μM to 33 μM.