1855-18-1Relevant academic research and scientific papers
TfOH-catalyzed synthesis of 3-aryl isoindolinones via a tandem reaction
Hu, Jiaxing,Qin, Hua-Li,Xu, Wengang,Li, Junli,Zhang, Fanglin,Zheng, Hua
, p. 15780 - 15783 (2014)
A convenient metal-free method for the synthesis of 3-aryl isoindolinones via TfOH catalyzed aromatic C-H functionalization of electron-rich arenes with 2-formylbenzonitriles is developed. This process provided a new efficient strategy for the synthesis of isoindolinone derivatives in good to high yields and regioselectivities by forming two bonds.
